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BBN might refer to:
- BBN Technologies, formerly Bolt, Beranek and Newman, a technology company in Cambridge, Massachusetts, best known for its work on packet switching technology and its construction of the Interface Message Processor - the first router
- Bayesian belief network a probabilistic graphical model that represents a set of random variables and their conditional independencies via a directed acyclic graph (DAG)
- Bible Broadcasting Network, a global Christian radio network headquartered in Charlotte, North Carolina
- Big Bang nucleosynthesis
- Big Brother Nigeria, a reality show which took place in Nigeria
- Brevard Business News
- Buckingham Browne & Nichols School (BB&N), a private school in Cambridge, Massachusetts
- 9-Borabicyclo[3.3.1]nonane (9-BBN), a reagent used in organic chemistry
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