Beta-3 adrenergic antagonist
A Beta-3 adrenergic antagonist (β3-adrenoceptor antagonist) is an adrenergic antagonist which blocks the Beta-3 adrenergic receptors of cells, with either high specificity (an antagonist which is selective for β3 adrenoceptors) like L-748,328, L-748,337 and SR 59230A or non-specifically (an antagonist for β3 and for β1 or β2 adrenoceptors) like the non-selective betablocker Carvedilol.[1]
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References[edit]
- ^ Candelore MR, Deng L, Tota L, Guan XM, Amend A, Liu Y, Newbold R, Cascieri MA, Weber AE (Aug 1999). "Potent and selective human beta(3)-adrenergic receptor antagonists". The Journal of Pharmacology and Experimental Therapeutics. 290 (2): 649–55. PMID 10411574.
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