Bone cell: Difference between revisions

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{{expert}}
There are five types of '''bone cells'''.

*[[Osteoblast]]s - These are commonly called bone-forming cells. They secrete [[osteoid]], which forms the [[bone matrix]]. They also begin [[mineralization]], and are unable to divide.
*[[Osteocyte]]s - A mature osteoblast which no longer secretes matrix, yet is surrounded by it. Maintains metabolism, and participates in nutrient/waste exchange via blood. Unable to divide.
*[[Osteoclast]]s - These function in resorption and degradation of existing bone, the opposite of osteoblasts! [[Monocytes]] [[(White blood cells)]] fuse together to create these huge cells, which are concentrated in the [[endosteum]].
*((Osteogenic))
*((bone-lining))

Although [[osteogenic]] or [[osteoprogenitor cells]] are commonly mentioned in bone literature, these do not appear to be a unique type of cell. Rather, osteoblasts derive from [[mesenchymal cell|mesenchymal stem cells]], which have shown the ability to differentiate into [[chondrocyte]]s and [[adipocyte]]s as well. Adipocytes are worm like substances that live and never move freely around and in the bone structure.

==References==
*Bone marrow mesenchymal cells: biological properties and clinical applications. PMID: [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11388742 11388742]
*Bone marrow stromal stem cells: nature, biology, and potential applications. PMID: [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11388742 11359943]
*[http://stemcells.nih.gov/info/scireport/appendixE.asp Stem cell information]


[[Category:Cell biology]]
[[Category:Skeletal system]]

{{cell-biology-stub}}

Revision as of 01:28, 10 December 2008