Bone cell
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There are five types of bone cells.
- Osteoblasts - These are commonly called bone-forming cells. They secrete osteoid, which forms the bone matrix. They also begin mineralization, and are unable to divide.
- Osteocytes - A mature osteoblast which no longer secretes matrix, yet is surrounded by it. Maintains metabolism, and participates in nutrient/waste exchange via blood. Unable to divide.
- Osteoclasts - These function in resorption and degradation of existing bone, the opposite of osteoblasts. Monocytes (a type of white blood cell) fuse together to create these huge cells, which are concentrated in the endosteum.
- Osteoprogenitors - Immature cells which differentiate to make osteoblasts. May divide.
- bone-lining- quiescent osteoblasts covering the bone [1]
Although osteogenic or osteoprogenitor cells are commonly mentioned in bone literature, these do not appear to be a unique type of cell. Rather, osteoblasts derive from mesenchymal stem cells, which have shown the ability to differentiate into chondrocytes and adipocytes as well.
[edit] Notes
- ^ Miller, Scott C.; Jee, Webster S. S. (1987). "The bone lining cell: A distinct phenotype?". Calcified Tissue International 41 (1): 1–5. doi:10.1007/BF02555122.
bone cells protect broken tissues
[edit] References
- Dominici M, Hofmann TJ, Horwitz EM (2001). "Bone marrow mesenchymal cells: biological properties and clinical applications". J. Biol. Regul. Homeost. Agents 15 (1): 28–37. PMID 11388742.
- Bianco P, Riminucci M, Gronthos S, Robey PG (2001). "Bone marrow stromal stem cells: nature, biology, and potential applications". Stem Cells 19 (3): 180–92. doi:10.1634/stemcells.19-3-180. PMID 11359943.
- Stem cell information
[edit] See also
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