Busseron was surveyed by George Calhoun in 1854. W. W. Harper, J. A. McClure and T.P. Emison were proprietors. It was a station on the Evansville & Terre Haute Railroad. As early as the 1920s, Busseron was not so much a town and just simply a railroad station.
^Brothers, Goodspeed (2010). History of knox and daviess counties, indiana. from the earliest time to the present; with biographical sketches, reminiscences, notes, etc.; together .. and its progress down to the formation of th. Nabu Press.