Butyrin
From Wikipedia, the free encyclopedia
| Butyrin | |
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1,3-Di(butanoyloxy)propan-2-yl butanoate |
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Other names
Tributyrin |
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| Identifiers | |
| CAS number | 60-01-5  |
| PubChem | 6050 |
| ChemSpider | 5827 |
| UNII | S05LZ624MF |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C15H26O6 |
| Molar mass | 302.36 g mol−1 |
| Appearance | Oily liquid with bitter taste[1] |
| Density | 1.032 g/cm3[1] |
| Melting point |
-75 °C, 198 K, -103 °F ([1]) |
| Boiling point |
305-310 °C, 578-583 K, 581-590 °F ([1]) |
| Solubility in water | Insoluble[1] |
| Hazards | |
| MSDS | Tributyrin MSDS, Fischer Scientific |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Butyrin, also known as tributyrin, is a triglyceride naturally present in butter. It is an ester composed of butyric acid and glycerol.[1] Among other things, it is used as an ingredient in making margarine. It is commonly occurring in butter and can be described as a liquid fat with an acrid taste.
Tributyrin is also used in microbiological laboratories to identify the bacterium Moraxella catarrhalis. [2]
Tributyrin is a stable and rapidly absorbed prodrug of butyric acid which enhances antiproliferative effects of dihydroxycholecalciferol in human colon cancer cells.[3]
[edit] References
- ^ a b c d e f Budavari, Susan, ed. (1996), The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th ed.), Merck, ISBN 0911910123
- ^ Pérez, José L.; Angeles Pulido, Florencia Pantozzi, Rogelio Martin (October 1990). "Butyrate esterase (4-methylumbelliferyl butyrate) spot test, a simple method for immediate identification of Moraxella (Branhamella) catarrhalis corrected" (PDF Reprint). Journal of Clinical Microbiology (Washington, DC: American Society for Microbiology) 28 (10): 2347–2348. ISSN 1098-660X. PMC 268174. PMID 2121784. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=268174.
- ^ Gaschott, Tanja; Dieter Steinhilber, Vladan Milovic, Jürgen Stein (June 2001). "Tributyrin, a Stable and Rapidly Absorbed Prodrug of Butyric Acid, Enhances Antiproliferative Effects of Dihydroxycholecalciferol in Human Colon Cancer Cells". The Journal of Nutrition (Bethesda, MD: The American Society for Nutritional Sciences) 131 (6): 1839–1843. ISSN 1541-6100. PMID 11385076. http://jn.nutrition.org/cgi/content/full/131/6/1839. Retrieved 2009-08-17.
