CRABP1

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Cellular retinoic acid binding protein 1
Protein CRABP1 PDB 1cbi.png
PDB rendering based on 1cbi.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols CRABP1 ; CRABP; CRABP-I; CRABPI; RBP5
External IDs OMIM180230 MGI88490 HomoloGene3222 ChEMBL: 2079 GeneCards: CRABP1 Gene
RNA expression pattern
PBB GE CRABP1 205350 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1381 12903
Ensembl ENSG00000166426 ENSMUSG00000032291
UniProt P29762 P62965
RefSeq (mRNA) NM_004378 NM_001284507
RefSeq (protein) NP_004369 NP_001271436
Location (UCSC) Chr 15:
78.63 – 78.64 Mb
Chr 9:
54.76 – 54.77 Mb
PubMed search [1] [2]

Cellular retinoic acid-binding protein 1 is a protein that in humans is encoded by the CRABP1 gene.[1][2]

A number of specific carrier proteins for members of the vitamin A family have been discovered. Cellular retinoic acid-binding protein is assumed to play an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid. CRABP1 is constitutively expressed and is believed to have different functions in the cell than the related CRABP2.[2]

References[edit]

  1. ^ Flagiello D, Apiou F, Gibaud A, Poupon MF, Dutrillaux B, Malfoy B (Jun 1997). "Assignment of the genes for cellular retinoic acid binding protein 1 (CRABP1) and 2 (CRABP2) to human chromosome band 15q24 and 1q21.3, respectively, by in situ hybridization". Cytogenet Cell Genet 76 (1–2): 17–8. doi:10.1159/000134502. PMID 9154115. 
  2. ^ a b "Entrez Gene: CRABP1 cellular retinoic acid binding protein 1". 

Further reading[edit]