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Cellular retinoic acid binding protein 1
Protein CRABP1 PDB 1cbi.png
PDB rendering based on 1cbi.
Available structures
PDB Ortholog search: PDBe, RCSB
External IDs OMIM180230 MGI88490 HomoloGene3222 IUPHAR: 2529 ChEMBL: 2079 GeneCards: CRABP1 Gene
RNA expression pattern
PBB GE CRABP1 205350 at tn.png
More reference expression data
Species Human Mouse
Entrez 1381 12903
Ensembl ENSG00000166426 ENSMUSG00000032291
UniProt P29762 P62965
RefSeq (mRNA) NM_004378 NM_001284507
RefSeq (protein) NP_004369 NP_001271436
Location (UCSC) Chr 15:
78.63 – 78.64 Mb
Chr 9:
54.76 – 54.77 Mb
PubMed search [1] [2]

Cellular retinoic acid-binding protein 1 is a protein that in humans is encoded by the CRABP1 gene.[1][2]

A number of specific carrier proteins for members of the vitamin A family have been discovered. Cellular retinoic acid-binding protein is assumed to play an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid. CRABP1 is constitutively expressed and is believed to have different functions in the cell than the related CRABP2.[2]


  1. ^ Flagiello D, Apiou F, Gibaud A, Poupon MF, Dutrillaux B, Malfoy B (Jun 1997). "Assignment of the genes for cellular retinoic acid binding protein 1 (CRABP1) and 2 (CRABP2) to human chromosome band 15q24 and 1q21.3, respectively, by in situ hybridization". Cytogenet Cell Genet 76 (1–2): 17–8. doi:10.1159/000134502. PMID 9154115. 
  2. ^ a b "Entrez Gene: CRABP1 cellular retinoic acid binding protein 1". 

Further reading[edit]