FLVCR1

Feline leukemia virus subgroup C cellular receptor 1
Identifiers
Symbols	FLVCR1; AXPC1; FLJ33420; FLVCR; MFSD7B; PCA; PCARP
External IDs	OMIM: 609144 MGI: 2444881 HomoloGene: 56661 GeneCards: FLVCR1 Gene
Gene Ontology Molecular function • receptor activity • transporter activity • protein binding • heme transporter activity • heme transporter activity • heme transporter activity Cellular component • plasma membrane • integral to plasma membrane Biological process • in utero embryonic development • transport • cellular iron ion homeostasis • multicellular organismal development • cell death • heme transport • heme transport • erythrocyte differentiation • limb morphogenesis • multicellular organism growth • embryonic digit morphogenesis • regulation of organ growth • spleen development • transmembrane transport • head morphogenesis • heme export Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	28982	226844
Ensembl	ENSG00000162769	ENSMUSG00000066595
UniProt	Q9Y5Y0	n/a
RefSeq (mRNA)	NM_014053.3	NM_001081259.1
RefSeq (protein)	NP_054772.1	NP_001074728.1
Location (UCSC)	Chr 1: 213.03 – 213.07 Mb	Chr 1: 192.83 – 192.85 Mb
PubMed search	[1]	[2]

Feline leukemia virus subgroup C receptor-related protein 1 is a protein that in humans is encoded by the FLVCR1 gene.

Further reading

• Lipovich L, Hughes AL, King MC, et al. (2002). "Genomic structure and evolutionary context of the human feline leukemia virus subgroup C receptor (hFLVCR) gene: evidence for block duplications and de novo gene formation within duplicons of the hFLVCR locus.". Gene 286 (2): 203–13. doi:10.1016/S0378-1119(02)00457-2. PMID 11943475. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Quigley JG, Yang Z, Worthington MT, et al. (2004). "Identification of a human heme exporter that is essential for erythropoiesis.". Cell 118 (6): 757–66. doi:10.1016/j.cell.2004.08.014. PMID 15369674. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Quigley JG, Gazda H, Yang Z, et al. (2006). "Investigation of a putative role for FLVCR, a cytoplasmic heme exporter, in Diamond-Blackfan anemia.". Blood Cells Mol. Dis. 35 (2): 189–92. doi:10.1016/j.bcmd.2005.01.005. PMID 15996880. 
• Brown JK, Fung C, Tailor CS (2006). "Comprehensive mapping of receptor-functioning domains in feline leukemia virus subgroup C receptor FLVCR1.". J. Virol. 80 (4): 1742–51. doi:10.1128/JVI.80.4.1742-1751.2006. PMC 1367145. PMID 16439531. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1367145.