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Superposition of the immunoglobulin domains of SARS-CoV-2 proteins ORF8 (blue) and ORF7a (orange), illustrating the structural similarity of their beta-sheet organization. Rendered with PyMol from chain A of PDB: 7JTL​ (ORF8, blue) and PDB: 7CI3​ (ORF7a, orange).

7JTL: Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein. Flower, T.G., Buffalo, C.Z., Hooy, R.M., Allaire, M., Ren, X., Hurley, J.H. (2021) Proc Natl Acad Sci U S A 118

PubMed: 33361333 DOI: 10.1073/pnas.2021785118

7CI3: Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14 + monocytes. Zhou, Z., Huang, C., Zhou, Z., Huang, Z., Su, L., Kang, S., Chen, X., Chen, Q., He, S., Rong, X., Xiao, F., Chen, J., Chen, S. (2021) iScience 24: 102187-102187

PubMed: 33615195 DOI: 10.1016/j.isci.2021.102187
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Author Opabinia regalis

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current04:53, 23 September 2021Thumbnail for version as of 04:53, 23 September 2021768 × 1,024 (292 KB)Opabinia regalis{{Information |Description=Superposition of the immunoglobulin domains of SARS-CoV-2 proteins ORF8 (blue) and ORF7a (orange), illustrating the structural similarity of their beta-sheet organization. Rendered with PyMol from chain A of {{PDB|7JTL}} (ORF8, blue) and {{PDB|7CI3}} (ORF7a, orange). 7JTL: Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein. Flower, T.G., Buffalo, C.Z., Hooy, R.M., Allaire, M., Ren, X., Hurley, J.H. (2021) Proc Natl Acad Sci U S A 118 PubMed: 3...

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