He lived in Venice, and preached at St. Mark's Cathedral. Besides Hypnerotomachia Poliphili, he definitely wrote an Italianepic poem called Delfili Somnium, the "Dream of Delfilo' which went unpublished in his lifetime and was not published until 1959. Colonna spent part of his life in the monastery of St. John and St. Paul in Venice, but the monastery was apparently not of the strictest observance and Colonna was granted leave to live outside its walls. In Ian Caldwell's and Dustin Thomason's book, The Rule of Four, Francesco Colonna is said to be a Roman, rather than a monk and the true author of the Hypnerotomachia Poliphili.
Colonna, Francesco, Hypnerotomachia: The Strife of Love in a Dreame, Translation by R.D., London, 1592. Facsimile ed., introd. by Lucy Gent, 1973, Scholars' Facsimiles & Reprints, ISBN 978-0-8201-1124-7.