Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Collart D, Ramsey-Ewing A, Bortell R et al. (1991). "Isolation and characterization of a cDNA from a human histone H2B gene which is reciprocally expressed in relation to replication-dependent H2B histone genes during HL60 cell differentiation". Biochemistry30 (6): 1610–7. doi:10.1021/bi00220a024. PMID1993178.
Jackson S, Brooks W, Jackson V (1994). "Dynamics of the interactions of histones H2A,H2B and H3,H4 with torsionally stressed DNA". Biochemistry33 (18): 5392–403. doi:10.1021/bi00184a006. PMID8180162.
Rodriguez P, Munroe D, Prawitt D et al. (1997). "Functional characterization of human nucleosome assembly protein-2 (NAP1L4) suggests a role as a histone chaperone". Genomics44 (3): 253–65. doi:10.1006/geno.1997.4868. PMID9325046.
Zhang Y, Sun ZW, Iratni R et al. (1998). "SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex". Mol. Cell1 (7): 1021–31. doi:10.1016/S1097-2765(00)80102-1. PMID9651585.
Becker W, Weber Y, Wetzel K et al. (1998). "Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases". J. Biol. Chem.273 (40): 25893–902. doi:10.1074/jbc.273.40.25893. PMID9748265.
Allen MP, Zeng C, Schneider K et al. (1999). "Growth arrest-specific gene 6 (Gas6)/adhesion related kinase (Ark) signaling promotes gonadotropin-releasing hormone neuronal survival via extracellular signal-regulated kinase (ERK) and Akt". Mol. Endocrinol.13 (2): 191–201. doi:10.1210/me.13.2.191. PMID9973250.
Piredda L, Farrace MG, Lo Bello M et al. (1999). "Identification of 'tissue' transglutaminase binding proteins in neural cells committed to apoptosis". FASEB J.13 (2): 355–64. PMID9973324.
Kawasaki H, Schiltz L, Chiu R et al. (2000). "ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation". Nature405 (6783): 195–200. doi:10.1038/35012097. PMID10821277.
Deng L, de la Fuente C, Fu P et al. (2001). "Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones". Virology277 (2): 278–95. doi:10.1006/viro.2000.0593. PMID11080476.
Freire J, Covelo G, Sarandeses C et al. (2001). "Identification of nuclear-import and cell-cycle regulatory proteins that bind to prothymosin alpha". Biochem. Cell Biol.79 (2): 123–31. doi:10.1139/bcb-79-2-123. PMID11310559.