Jod-Basedow phenomenon
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The Jod-Basedow effect is hyperthyroidism following administration of iodine or iodide,[1] either as a dietary supplement or as contrast medium.
This phenomenon is an iodine-induced hyperthyroidism, typically presenting in a patient with endemic goiter who then relocates to an iodine-abundant geographical area.
It is named for Karl Adolph von Basedow, a German physician and the German word for iodine, "jod". It is the opposite of the Wolff-Chaikoff effect.
It may be a side effect of administration of amiodarone, an antiarrhythmic drug (Vaughn-Williams class III)
[edit] References
- ^ El-Shirbiny AM, Stavrou SS, Dnistrian A, Sonenberg M, Larson SM, Divgi CR (November 1997). "Jod-Basedow syndrome following oral iodine and radioiodinated-antibody administration". J. Nucl. Med. 38 (11): 1816–7. PMID 9374363. http://jnm.snmjournals.org/cgi/pmidlookup?view=long&pmid=9374363.
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