KIFC1

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Kinesin family member C1
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols KIFC1 ; HSET; KNSL2
External IDs OMIM603763 MGI109596 HomoloGene83229 GeneCards: KIFC1 Gene
RNA expression pattern
PBB GE KIFC1 209680 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 3833 16580
Ensembl ENSG00000056678 ENSMUSG00000024301
UniProt Q9BW19 Q9QWT9
RefSeq (mRNA) NM_002263 NM_016761
RefSeq (protein) NP_002254 NP_444403
Location (UCSC) Chr 6:
33.36 – 33.38 Mb
Chr 17:
26.92 – 26.93 Mb
PubMed search [1] [2]

Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene.[1][2]

The protein KifC1 is a member of kinesin-14 family. KifC1 consists of C-terminal motor domain, superhelical stalk and N-terminal tail domain. Tail and motor domains contain microtubule-binding sites. This kinesin moves towards the minus-end of microtubule and has an ability to slide or crosslink microtubules. KifC1 functions during mitotic spindle formation.

References[edit]

  1. ^ Ando A, Kikuti YY, Kawata H, Okamoto N, Imai T, Eki T, Yokoyama K, Soeda E, Ikemura T (Feb 1994). "Cloning of a new kinesin-related gene located at the centromeric end of the human MHC region". Immunogenetics 39 (3): 194–200. doi:10.1007/bf00241260. PMID 8276466. 
  2. ^ "Entrez Gene: KIFC1 kinesin family member C1". 

Further reading[edit]