LEO1
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| Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | LEO1; RDL | ||||||||||||
| External IDs | OMIM: 610507 MGI: 2685031 HomoloGene: 43710 GeneCards: LEO1 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 123169 | 235497 | |||||||||||
| Ensembl | ENSG00000166477 | ENSMUSG00000042487 | |||||||||||
| UniProt | Q8WVC0 | Q5XJE5 | |||||||||||
| RefSeq (mRNA) | NM_138792.2 | NM_001006122.1 | |||||||||||
| RefSeq (protein) | NP_620147.1 | NP_001034611.1 | |||||||||||
| Location (UCSC) | Chr 15: 52.23 – 52.26 Mb |
Chr 9: 75.29 – 75.31 Mb |
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| PubMed search | [1] | [2] | |||||||||||
RNA polymerase-associated protein LEO1 is an enzyme that in humans is encoded by the LEO1 gene.[1][2]
[edit] References
- ^ Rozenblatt-Rosen O, Hughes CM, Nannepaga SJ, Shanmugam KS, Copeland TD, Guszczynski T, Resau JH, Meyerson M (Jan 2005). "The Parafibromin Tumor Suppressor Protein Is Part of a Human Paf1 Complex". Mol Cell Biol 25 (2): 612–20. doi:10.1128/MCB.25.2.612-620.2005. PMC 543415. PMID 15632063. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=543415.
- ^ "Entrez Gene: LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=123169.
[edit] Further reading
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=514446.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Zhao L, Tong T, Zhang Z (2005). "Expression of the Leo1-like domain of replicative senescence down-regulated Leo1-like (RDL) protein promotes senescence of 2BS fibroblasts". FASEB J. 19 (6): 521–32. doi:10.1096/fj.04-2689com. PMID 15791002.
- Mosimann C, Hausmann G, Basler K (2006). "Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo". Cell 125 (2): 327–41. doi:10.1016/j.cell.2006.01.053. PMID 16630820.
- Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
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