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MA-10 cell

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MA-10 cells are a model cell line derived from the mouse Leydig cell tumor used in biomedical research.[1] The cell line is a luteinizing hormone-dependent steroidogenic cell line that was generated from a mice inbred strain C57BL/6J.[2] MA-10 cells are the most widely used of Leydig cell lines, and contributed much to our knowledge in Leydig cell steroid formation and regulation.[3]

References

  1. ^ Rahman, Nafis A; Huhtaniemi, Ilpo T (30 December 2004). "Testicular cell lines". Mol Cell Endocrinol. 228 (1–2): 53–65. doi:10.1016/j.mce.2003.05.001. PMID 15541572.
  2. ^ ASCOLI, MARIO (1 Jan 1981). "Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptors and steroidogenic responses". Endocrinology. 108 (1): 88–95. doi:10.1210/endo-108-1-88. PMID 6257492.
  3. ^ Zirkin BR, Papadopoulos V (2018). "Leydig cells: formation, function, and regulation". Biology of Reproduction. 99 (1): 101–11. doi:10.1093/biolre/ioy059. PMC 6044347. PMID 29566165.
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