MAGEH1
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| Melanoma antigen family H, 1 | |||||||||||
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| Identifiers | |||||||||||
| Symbols | MAGEH1; APR-1; APR1; MAGEH | ||||||||||
| External IDs | OMIM: 300548 MGI: 1922875 HomoloGene: 8545 GeneCards: MAGEH1 Gene | ||||||||||
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| RNA expression pattern | |||||||||||
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| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | 28986 | 75625 | |||||||||
| Ensembl | ENSG00000187601 | ENSMUSG00000047238 | |||||||||
| UniProt | Q9H213 | Q9NWG9 | |||||||||
| RefSeq (mRNA) | NM_014061.3 | NM_023788.3 | |||||||||
| RefSeq (protein) | NP_054780.2 | NP_076277.1 | |||||||||
| Location (UCSC) | Chr X: 55.48 – 55.48 Mb |
Chr X: 149.47 – 149.47 Mb |
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| PubMed search | [1] | [2] | |||||||||
Melanoma-associated antigen H1 is a protein that in humans is encoded by the MAGEH1 gene.[1][2][3]
This gene is thought to be involved in apoptosis. Multiple polyadenylation sites have been found for this gene.[3]
[edit] Interactions
MAGEH1 has been shown to interact with Low affinity nerve growth factor receptor.[1]
[edit] References
- ^ a b Tcherpakov M, Bronfman FC, Conticello SG, Vaskovsky A, Levy Z, Niinobe M, Yoshikawa K, Arenas E, Fainzilber M (Dec 2002). "The p75 neurotrophin receptor interacts with multiple MAGE proteins". J Biol Chem 277 (51): 49101–4. doi:10.1074/jbc.C200533200. PMID 12414813.
- ^ Lucas S, De Smet C, Arden KC, Viars CS, Lethe B, Lurquin C, Boon T (Mar 1998). "Identification of a new MAGE gene with tumor-specific expression by representational difference analysis". Cancer Res 58 (4): 743–52. PMID 9485030.
- ^ a b "Entrez Gene: MAGEH1 melanoma antigen family H, 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=28986.
[edit] Further reading
- Zhu F, Yan W, Zhao ZL, et al. (2001). "Improved PCR-based subtractive hybridization strategy for cloning differentially expressed genes.". BioTechniques 29 (2): 310–3. PMID 10948432.
- Chomez P, De Backer O, Bertrand M, et al. (2001). "An overview of the MAGE gene family with the identification of all human members of the family.". Cancer Res. 61 (14): 5544–51. PMID 11454705.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Goehler H, Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell 15 (6): 853–65. doi:10.1016/j.molcel.2004.09.016. PMID 15383276.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature 434 (7031): 325–37. doi:10.1038/nature03440. PMC 2665286. PMID 15772651. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2665286.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Fu H, Yang G, Lu F, et al. (2006). "Transcriptional up-regulation of restin by all-trans retinoic acid through STAT1 in cancer cell differentiation process". Biochem. Biophys. Res. Commun. 343 (4): 1009–16. doi:10.1016/j.bbrc.2006.02.176. PMID 16574066.
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