From Wikipedia, the free encyclopedia
Jump to: navigation, search
Protein MTPN PDB 1myo.png
PDB rendering based on 1myo.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols MTPN ; GCDP; V-1
External IDs OMIM606484 MGI99445 HomoloGene40607 GeneCards: MTPN Gene
RNA expression pattern
PBB GE MTPN gnf1h09064 at tn.png
More reference expression data
Species Human Mouse
Entrez 136319 14489
Ensembl ENSG00000105887 ENSMUSG00000029840
UniProt P58546 P62774
RefSeq (mRNA) NM_145808 NM_008098
RefSeq (protein) NP_665807 NP_032124
Location (UCSC) Chr 7:
135.61 – 135.66 Mb
Chr 6:
35.51 – 35.54 Mb
PubMed search [1] [2]

Myotrophin is a protein that in humans is encoded by the MTPN gene.[1][2]


MTPN has been shown to interact with RELA[3] and REL.[3]


  1. ^ Mitra S, Timur AA, Gupta S, Wang Q, Sen S (July 2001). "Assignment of myotrophin to human chromosome band 7q33→q35 by in situ hybridization". Cytogenet Cell Genet 93 (1–2): 151–2. doi:10.1159/000056974. PMID 11474205. 
  2. ^ "Entrez Gene: MTPN myotrophin". 
  3. ^ a b Knuefermann, Pascal; Chen Peter; Misra Arunima; Shi Shu-Ping; Abdellatif Maha; Sivasubramanian Natarajan (June 2002). "Myotrophin/V-1, a protein up-regulated in the failing human heart and in postnatal cerebellum, converts NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers". J. Biol. Chem. (United States) 277 (26): 23888–97. doi:10.1074/jbc.M202937200. ISSN 0021-9258. PMID 11971907. 

Further reading[edit]