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Nerve growth factor receptor (TNFRSF16) associated protein 1
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols NGFRAP1 ; BEX3; Bex; DXS6984E; HGR74; NADE
External IDs OMIM300361 MGI1338016 HomoloGene7642 GeneCards: NGFRAP1 Gene
RNA expression pattern
PBB GE NGFRAP1 217963 s at tn.png
More reference expression data
Species Human Mouse
Entrez 27018 12070
Ensembl ENSG00000166681 ENSMUSG00000046432
UniProt Q00994 Q9WTZ9
RefSeq (mRNA) NM_001282674 NM_001110233
RefSeq (protein) NP_001269603 NP_001103703
Location (UCSC) Chr X:
102.63 – 102.63 Mb
Chr X:
136.27 – 136.27 Mb
PubMed search [1] [2]

Protein BEX3 is a protein that in humans is encoded by the NGFRAP1 gene.[1][2][3]


NGFRAP1 has been shown to interact with YWHAE[4] and Low affinity nerve growth factor receptor.[1]


  1. ^ a b Mukai J, Hachiya T, Shoji-Hoshino S, Kimura MT, Nadano D, Suvanto P, Hanaoka T, Li Y, Irie S, Greene LA, Sato TA (Jul 2000). "NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR". J Biol Chem 275 (23): 17566–70. doi:10.1074/jbc.C000140200. PMID 10764727. 
  2. ^ Rapp G, Freudenstein J, Klaudiny J, Mucha J, Wempe F, Zimmer M, Scheit KH (Dec 1990). "Characterization of three abundant mRNAs from human ovarian granulosa cells". DNA Cell Biol 9 (7): 479–85. doi:10.1089/dna.1990.9.479. PMID 2171551. 
  3. ^ "Entrez Gene: NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1". 
  4. ^ Kimura, M T; Irie S; Shoji-Hoshino S; Mukai J; Nadano D; Oshimura M; Sato T A (May 2001). "14-3-3 is involved in p75 neurotrophin receptor-mediated signal transduction". J. Biol. Chem. (United States) 276 (20): 17291–300. doi:10.1074/jbc.M005453200. ISSN 0021-9258. PMID 11278287. 

Further reading[edit]