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Nidogen 2 (osteonidogen)
Symbols NID2 ; NID-2
External IDs OMIM605399 MGI1298229 HomoloGene40575 GeneCards: NID2 Gene
RNA expression pattern
PBB GE NID2 204114 at tn.png
More reference expression data
Species Human Mouse
Entrez 22795 18074
Ensembl ENSG00000087303 ENSMUSG00000021806
UniProt Q14112 O88322
RefSeq (mRNA) NM_007361 NM_008695
RefSeq (protein) NP_031387 NP_032721
Location (UCSC) Chr 14:
52.47 – 52.54 Mb
Chr 14:
19.75 – 19.81 Mb
PubMed search [1] [2]

Nidogen-2 is a protein that in humans is encoded by the NID2 gene.[1][2]

Basement membranes, which are composed of type IV collagens (see MIM 120130), laminins (see LAMC1; MIM 150290), perlecan (HSPG2; MIM 142461), and nidogen (see NID1; MIM 131390), are thin pericellular protein matrices that control a large number of cellular activities, including adhesion, migration, differentiation, gene expression, and apoptosis [supplied by OMIM].[2]


  1. ^ Kohfeldt E, Sasaki T, Gohring W, Timpl R (Oct 1998). "Nidogen-2: a new basement membrane protein with diverse binding properties". J Mol Biol 282 (1): 99–109. doi:10.1006/jmbi.1998.2004. PMID 9733643. 
  2. ^ a b "Entrez Gene: NID2 nidogen 2 (osteonidogen)". 

Further reading[edit]