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NACHT and WD repeat domain containing 1
Symbols NWD1 ; MGC134940
External IDs MGI2442268 HomoloGene72261 GeneCards: NWD1 Gene
Species Human Mouse
Entrez 284434 319555
Ensembl ENSG00000188039 ENSMUSG00000048148
UniProt Q149M9 E0CX99
RefSeq (mRNA) NM_001007525 NM_001159403
RefSeq (protein) NP_001007526 NP_795914
Location (UCSC) Chr 19:
16.83 – 16.93 Mb
Chr 8:
72.65 – 72.71 Mb
PubMed search [1] [2]

NWD1, short for NACHT and WD repeat domain containing 1, is a gene found in vertebrates, which encodes a protein that contains a NACHT domain and a WD40 repeat domain. It was originally identified during a search for immune system genes in zebrafish as a protein coding sequence related to APAF1; orthologs were subsequently identified in mammalian species.[1] The NWD1 gene of humans is located on chromosome 19. The function of the NWD1 protein is currently unknown.


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