Nathaniel P. "Nat" Hudson (January 12, 1859 – March 14, 1928) was an American Major League Baseball pitcher for the St. Louis Browns from 1886 to 1889.
Hudson started his professional baseball career at the age of 15, with Quincy of the Northwestern League. In 1886, he signed with the Browns and went 16–10 for them. He also started and won one game in that year's "World Series" against the National League's Chicago White Stockings.
Hudson had his best season in 1888, going 25–10 with a 2.54 earned run average and leading the American Association in winning percentage. His career record was 48 wins and 26 losses.
On July 17, 1889, Hudson was traded to the Louisville Colonels in exchange for Toad Ramsey; however, he refused to report to Louisville and never played another major league game. On August 18, he was sold for $1,000 to the Minneapolis Millers of the Western Association. He played two seasons for them before retiring.
Hudson died at the age of 69 in his hometown of Chicago, Illinois. He is interred at Rosehill Cemetery.