Neutrophilic dermatosis of the dorsal hands
| Neutrophilic dermatosis of the dorsal hands | |
|---|---|
| Other names | Pustular vasculitis of the dorsal hands |
| Specialty | Dermatology |
Neutrophilic dermatosis of the dorsal hands (NDDH) is a skin condition that presents with edematous pustular or ulcerative nodules or plaques localized to the dorsal hands.[1]: 146 [2]
Signs and symptoms[edit]
Neutrophilic dermatosis of the dorsal hands is characterized by bullae, pustules, and delicate erythematous plaques on the hands' dorsa.[3]
Causes[edit]
Neutrophilic dermatosis of the dorsal hands is often associated with other conditions. Hematological disorders such as myelodysplastic syndrome and plasma cell dyscrasias are common.[3]
Diagnosis[edit]
The histopathology of NDDH lesions shows a dense neutrophil infiltrate in the dermis, which is typically linked to leukocytoclastic debris and subepidermal edema.[4]
Treatment[edit]
Systemic corticosteroids are the main method of treatment.[3]
See also[edit]
References[edit]
- ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
- ^ Dicaudo, David J.; Connolly, Suzanne M. (2002). "Neutrophilic Dermatosis (Pustular Vasculitis) of the Dorsal Hands". Archives of Dermatology. 138 (3): 361–365. doi:10.1001/archderm.138.3.361. PMID 11902987.
- ^ a b c Micallef, Daniel; Bonnici, Maria; Pisani, David; Boffa, Michael J. (2023). "Neutrophilic dermatosis of the dorsal hands: A review of 123 cases". Journal of the American Academy of Dermatology. 88 (6). Elsevier BV: 1338–1344. doi:10.1016/j.jaad.2019.08.070. ISSN 0190-9622. PMID 31499154. S2CID 202412220.
- ^ Kaur, S; Gupta, D; Garg, B; Sood, N (2015). "Neutrophilic dermatosis of dorsal hands". Indian Dermatology Online Journal. 6 (1). Medknow: 42–45. doi:10.4103/2229-5178.148940. ISSN 2229-5178. PMC 4314889. PMID 25657918.
Further reading[edit]
- DEL POZO, Jesús; SACRISTÁN, Felipe; MARTÍNEZ, Walter; PARADELA, Sabela; FERNÁNDEZ-JORGE, Beatriz; FONSECA, Eduardo (March 9, 2007). "Neutrophilic dermatosis of the hands: Presentation of eight cases and review of the literature". The Journal of Dermatology. 34 (4). Wiley: 243–247. doi:10.1111/j.1346-8138.2007.00261.x. ISSN 0385-2407. PMID 17352721. S2CID 34488900.
- Galaria, Noreen A.; Junkins-Hopkins, Jacqueline M.; Kligman, Douglas; James, William D. (2000). "Neutrophilic dermatosis of the dorsal hands: Pustular vasculitis revisited". Journal of the American Academy of Dermatology. 43 (5). Elsevier BV: 870–874. doi:10.1067/mjd.2000.109286. ISSN 0190-9622. PMID 11050599.