Nevus cell

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Nevus cells are a variant of melanocytes.[1]:684 They are larger than typical melanocytes, do not have dendrites, and have more abundant cytoplasm with coarse granules.[2] They are usually located at the dermoepidermal junction or in the dermis of the skin. Dermal nevus cells can be further classified: type A (epithelioid) dermal nevus cells mature into type B (lymphocytoid) dermal nevus cells which mature further into type C (neuroid) dermal nevus cells, through a process involving downwards migration.[2]

Nevus cells are the primary component of a melanocytic nevus.[3]

Nevus cells can also be found in lymph nodes[4] and the thymus.[5]

References[edit]

  1. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. 
  2. ^ a b Habif, Thomas P. (2010). Clinical Dermatology, 5th ed. Mosby. p. 847. ISBN 978-0-7234-3541-9. 
  3. ^ "nevus cell" at Dorland's Medical Dictionary
  4. ^ Biddle DA, Evans HL, Kemp BL, et al. (May 2003). "Intraparenchymal nevus cell aggregates in lymph nodes: a possible diagnostic pitfall with malignant melanoma and carcinoma". Am. J. Surg. Pathol. 27 (5): 673–81. doi:10.1097/00000478-200305000-00011. PMID 12717252. 
  5. ^ Parker JR, Ro JY, Ordóñez NG (March 1999). "Benign nevus cell aggregates in the thymus: a case report". Mod. Pathol. 12 (3): 329–32. PMID 10102620.