PIGB

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Phosphatidylinositol glycan anchor biosynthesis, class B
Identifiers
Symbols PIGB ; GPI-MT-III; PIG-B
External IDs OMIM604122 MGI1891825 HomoloGene3570 GeneCards: PIGB Gene
RNA expression pattern
PBB GE PIGB 205452 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 9488 55981
Ensembl ENSG00000069943 ENSMUSG00000079469
UniProt Q92521 Q9JJQ0
RefSeq (mRNA) NM_004855 NM_018889
RefSeq (protein) NP_004846 NP_061377
Location (UCSC) Chr 15:
55.61 – 55.65 Mb
Chr 9:
73.01 – 73.04 Mb
PubMed search [1] [2]

GPI mannosyltransferase 3 is an enzyme that in humans is encoded by the PIGB gene.[1][2]

This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases.[2]

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