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Protein phosphatase 6, catalytic subunit
Symbols PPP6C ; PP6; PP6C
External IDs OMIM612725 MGI1915107 HomoloGene68273 GeneCards: PPP6C Gene
EC number
RNA expression pattern
PBB GE PPP6C 203529 at tn.png
PBB GE PPP6C 206174 s at tn.png
More reference expression data
Species Human Mouse
Entrez 5537 67857
Ensembl ENSG00000119414 ENSMUSG00000026753
UniProt O00743 Q9CQR6
RefSeq (mRNA) NM_001123355 NM_024209
RefSeq (protein) NP_001116827 NP_077171
Location (UCSC) Chr 9:
125.15 – 125.19 Mb
Chr 2:
39.19 – 39.23 Mb
PubMed search [1] [2]

Serine/threonine-protein phosphatase 6 catalytic subunit is an enzyme that in humans is encoded by the PPP6C gene.[1][2]


PPP6C has been shown to interact with IGBP1.[3][4]


  1. ^ Bastians H, Krebber H, Vetrie D, Hoheisel J, Lichter P, Ponstingl H, Joos S (Jul 1997). "Localization of the novel serine/threonine protein phosphatase 6 gene (PPP6C) to human chromosome Xq22.3". Genomics 41 (2): 296–7. doi:10.1006/geno.1997.4640. PMID 9143513. 
  2. ^ "Entrez Gene: PPP6C protein phosphatase 6, catalytic subunit". 
  3. ^ Gingras, Anne-Claude; Caballero Michael; Zarske Marcel; Sanchez Amy; Hazbun Tony R; Fields Stanley; Sonenberg Nahum; Hafen Ernst; Raught Brian; Aebersold Ruedi (Nov 2005). "A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity". Mol. Cell Proteomics (United States) 4 (11): 1725–40. doi:10.1074/mcp.M500231-MCP200. ISSN 1535-9476. PMID 16085932. 
  4. ^ Chen, J; Peterson R T; Schreiber S L (Jun 1998). "Alpha 4 associates with protein phosphatases 2A, 4, and 6". Biochem. Biophys. Res. Commun. (UNITED STATES) 247 (3): 827–32. doi:10.1006/bbrc.1998.8792. ISSN 0006-291X. PMID 9647778. 

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