Parakeratosis
Parakeratosis is a mode of keratinization characterized by the retention of nuclei in the stratum corneum. On mucous membranes, parakeratosis is normal.[1]
Parakeratosis: The orderly but abnormal keratinization of cells so that the keratin layer consists of plump nucleated keratinized cells instead of annular squames. It is associated with the thinning or loss of the granular layer and is usually seen in diseases of increased cell turnover, whether inflammatory or neoplastic.Granular parakeratosis (originally termed axillary granular parakeratosis) is an idiopathic, benign, nondisabling cutaneous disease that manifests with intertriginous erythematous, brown or red, scaly or keratotic papules and plaques. It presents in all age groups and has no established clinical associations.[2]
[edit] See also
[edit] References
- ^ Kumar, Vinay; Fausto, Nelson; Abbas, Abul (2010) Robbins & Cotran Pathologic Basis of Disease (8th ed.). Saunders. Page 1170. ISBN 9781416031215.
- ^ Scheinfeld NS, Mones J. Granular parakeratosis: pathologic and clinical correlation of 18 cases of granular parakeratosis. J Am Acad Dermatol. 2005;52:863-7. PMID 15858479
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