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Pauci-immune (pauci- Latin: few, little) is a general term used to refer to a form of vasculitis that is associated with minimal evidence of hypersensitivity upon immunofluorescence and a lack of Anti-glomerular basement membrane antibody.

They can be associated with antineutrophil cytoplasmic antibodies (ANCA).[1]

In some cases, Pauci-immune crescentic glomerulonephritis is a component of a systemic vasculitis such as Microscopic polyangiitis, Churg–Strauss syndrome or Granulomatosis with polyangiitis.[2] In many cases however, it is limited to the kidney and is thus called idiopathic.

Peak incidences in 50 -60 year olds symptoms include; intermittent fever / weight loss / shortness of breath/ joint pain.

See also[edit]


  1. ^ Bollée G, Noël LH, Suarez F et al. (June 2009). "Pauci-immune crescentic glomerulonephritis associated with ANCA of IgA class". Am. J. Kidney Dis. 53 (6): 1063–7. doi:10.1053/j.ajkd.2008.10.039. PMID 19084310. 
  2. ^ "Final Diagnosis -- Case 51". Retrieved 2009-06-08. 

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