Pauci-immune (pauci- Latin: few, little) is a general term used to refer to a form of vasculitis that is associated with minimal evidence of hypersensitivity upon immunofluorescence and a lack of Anti-glomerular basement membrane antibody.
In some cases, Pauci-immune crescentic glomerulonephritis is a component of a systemic vasculitis such as Microscopic polyangiitis, Churg–Strauss syndrome or Granulomatosis with polyangiitis. In many cases however, it is limited to the kidney and is thus called idiopathic.
peak incidences in 50 -60 year olds symptoms include; intermittent fever / weight loss / dyspnea / arthalagia
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