RAB1A
From Wikipedia, the free encyclopedia
| RAB1A, member RAS oncogene family | |||||||||||||
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 PDB rendering based on 2fol. |
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| Identifiers | |||||||||||||
| Symbols | RAB1A; DKFZp564B163; RAB1; YPT1 | ||||||||||||
| External IDs | OMIM: 179508 MGI: 97842 HomoloGene: 36154 GeneCards: RAB1A Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 5861 | 19324 | |||||||||||
| Ensembl | ENSG00000138069 | ENSMUSG00000020149 | |||||||||||
| UniProt | P62820 | Q0PD67 | |||||||||||
| RefSeq (mRNA) | NM_004161.4 | NM_008996.3 | |||||||||||
| RefSeq (protein) | NP_004152.1 | NP_033022.1 | |||||||||||
| Location (UCSC) | Chr 2: 65.3 – 65.36 Mb |
Chr 11: 20.1 – 20.13 Mb |
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| PubMed search | [1] | [2] | |||||||||||
Ras-related protein Rab-1A is a protein that in humans is encoded by the RAB1A gene.[1][2]
[edit] Interactions
RAB1A has been shown to interact with CHM,[3] GOLGA5,[4][5] CHML,[3][6] RABAC1,[7][8] MICAL1[9] and GOLGA2.[9][10][11]
[edit] References
- ^ Zahraoui A, Touchot N, Chardin P, Tavitian A (Aug 1989). "The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion". J Biol Chem 264 (21): 12394–401. PMID 2501306.
- ^ "Entrez Gene: RAB1A RAB1A, member RAS oncogene family". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5861.
- ^ a b Cremers, F P; Armstrong S A, Seabra M C, Brown M S, Goldstein J L (Jan. 1994). "REP-2, a Rab escort protein encoded by the choroideremia-like gene". J. Biol. Chem. (UNITED STATES) 269 (3): 2111–7. ISSN 0021-9258. PMID 8294464.
- ^ Satoh, Ayano; Wang Yanzhuang, Malsam Jörg, Beard Matthew B, Warren Graham (Mar. 2003). "Golgin-84 is a rab1 binding partner involved in Golgi structure". Traffic (Denmark) 4 (3): 153–61. doi:10.1034/j.1600-0854.2003.00103.x. ISSN 1398-9219. PMID 12656988.
- ^ Diao, Aipo; Rahman Dinah, Pappin Darryl J C, Lucocq John, Lowe Martin (Jan. 2003). "The coiled-coil membrane protein golgin-84 is a novel rab effector required for Golgi ribbon formation". J. Cell Biol. (United States) 160 (2): 201–12. doi:10.1083/jcb.200207045. ISSN 0021-9525. PMC 2172652. PMID 12538640. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2172652.
- ^ Anant, J S; Desnoyers L, Machius M, Demeler B, Hansen J C, Westover K D, Deisenhofer J, Seabra M C (Sep. 1998). "Mechanism of Rab geranylgeranylation: formation of the catalytic ternary complex". Biochemistry (UNITED STATES) 37 (36): 12559–68. doi:10.1021/bi980881a. ISSN 0006-2960. PMID 9730828.
- ^ Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (Oct. 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- ^ Martincic, I; Peralta M E, Ngsee J K (Oct. 1997). "Isolation and characterization of a dual prenylated Rab and VAMP2 receptor". J. Biol. Chem. (UNITED STATES) 272 (43): 26991–8. doi:10.1074/jbc.272.43.26991. ISSN 0021-9258. PMID 9341137.
- ^ a b Weide, Thomas; Teuber Julia, Bayer Michael, Barnekow Angelika (Jun. 2003). "MICAL-1 isoforms, novel rab1 interacting proteins". Biochem. Biophys. Res. Commun. (United States) 306 (1): 79–86. doi:10.1016/S0006-291X(03)00918-5. ISSN 0006-291X. PMID 12788069.
- ^ Valsdottir, R; Hashimoto H, Ashman K, Koda T, Storrie B, Nilsson T (Nov. 2001). "Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER". FEBS Lett. (Netherlands) 508 (2): 201–9. doi:10.1016/S0014-5793(01)02993-3. ISSN 0014-5793. PMID 11718716.
- ^ Short, B; Preisinger C, Körner R, Kopajtich R, Byron O, Barr F A (Dec. 2001). "A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic". J. Cell Biol. (United States) 155 (6): 877–83. doi:10.1083/jcb.200108079. ISSN 0021-9525. PMC 2150909. PMID 11739401. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2150909.
[edit] Further reading
- Bailly E, McCaffrey M, Touchot N et al (1991). "Phosphorylation of two small GTP-binding proteins of the Rab family by p34cdc2". Nature 350 (6320): 715–8. doi:10.1038/350715a0. PMID 1902553.
- Farnsworth CC, Seabra MC, Ericsson LH et al (1995). "Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A". Proc. Natl. Acad. Sci. U.S.A. 91 (25): 11963–7. doi:10.1073/pnas.91.25.11963. PMC 45356. PMID 7991565. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=45356.
- Cremers FP, Armstrong SA, Seabra MC et al (1994). "REP-2, a Rab escort protein encoded by the choroideremia-like gene". J. Biol. Chem. 269 (3): 2111–7. PMID 8294464.
- Karniguian A, Zahraoui A, Tavitian A (1993). "Identification of small GTP-binding rab proteins in human platelets: thrombin-induced phosphorylation of rab3B, rab6, and rab8 proteins". Proc. Natl. Acad. Sci. U.S.A. 90 (16): 7647–51. doi:10.1073/pnas.90.16.7647. PMC 47199. PMID 8356066. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=47199.
- Wedemeyer N, Lengeling A, Ronsiek M et al (1997). "YAC contigs of the Rab1 and wobbler (wr) spinal muscular atrophy gene region on proximal mouse chromosome 11 and of the homologous region on human chromosome 2p". Genomics 32 (3): 447–54. doi:10.1006/geno.1996.0140. PMID 8838809.
- Martincic I, Peralta ME, Ngsee JK (1997). "Isolation and characterization of a dual prenylated Rab and VAMP2 receptor". J. Biol. Chem. 272 (43): 26991–8. doi:10.1074/jbc.272.43.26991. PMID 9341137.
- Anant JS, Desnoyers L, Machius M et al (1999). "Mechanism of Rab geranylgeranylation: formation of the catalytic ternary complex". Biochemistry 37 (36): 12559–68. doi:10.1021/bi980881a. PMID 9730828.
- Bao S, Zhu J, Garvey WT (1999). "Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects". Horm. Metab. Res. 30 (11): 656–62. doi:10.1055/s-2007-978953. PMID 9918381.
- Allan BB, Moyer BD, Balch WE (2000). "Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion". Science 289 (5478): 444–8. doi:10.1126/science.289.5478.444. PMID 10903204.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=310948.
- Wiemann S, Weil B, Wellenreuther R et al (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=311072.
- Simpson JC, Wellenreuther R, Poustka A et al (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1083732.
- Moyer BD, Allan BB, Balch WE (2001). "Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis--Golgi tethering". Traffic 2 (4): 268–76. doi:10.1034/j.1600-0854.2001.1o007.x. PMID 11285137.
- Muslin AJ (2002). "Road Rage: Cardiac Rab1 and ER-to-Golgi Traffic". Circ. Res. 89 (12): 1087–8. PMID 11739271.
- Short B, Preisinger C, Körner R et al (2002). "A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic". J. Cell Biol. 155 (6): 877–83. doi:10.1083/jcb.200108079. PMC 2150909. PMID 11739401. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2150909.
- Strausberg RL, Feingold EA, Grouse LH et al (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Diao A, Rahman D, Pappin DJ et al (2003). "The coiled-coil membrane protein golgin-84 is a novel rab effector required for Golgi ribbon formation". J. Cell Biol. 160 (2): 201–12. doi:10.1083/jcb.200207045. PMC 2172652. PMID 12538640. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2172652.
- Satoh A, Wang Y, Malsam J et al (2003). "Golgin-84 is a rab1 binding partner involved in Golgi structure". Traffic 4 (3): 153–61. doi:10.1034/j.1600-0854.2003.00103.x. PMID 12656988.
- Weide T, Teuber J, Bayer M, Barnekow A (2003). "MICAL-1 isoforms, novel rab1 interacting proteins". Biochem. Biophys. Res. Commun. 306 (1): 79–86. doi:10.1016/S0006-291X(03)00918-5. PMID 12788069.
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