RAPH1

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Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols RAPH1 ; ALS2CR18; ALS2CR9; LPD; PREL-2; PREL2; RMO1; RalGDS/AF-6
External IDs OMIM609035 MGI1924550 HomoloGene71030 GeneCards: RAPH1 Gene
Orthologs
Species Human Mouse
Entrez 65059 77300
Ensembl ENSG00000173166 ENSMUSG00000026014
UniProt Q70E73 F2Z3U3
RefSeq (mRNA) NM_025252 NM_001045513
RefSeq (protein) NP_976241 NP_001038978
Location (UCSC) Chr 2:
204.26 – 204.4 Mb
Chr 1:
60.48 – 60.57 Mb
PubMed search [1] [2]

Ras-associated and pleckstrin homology domains-containing protein 1 is a protein that in humans is encoded by the RAPH1 gene.[1]


References[edit]

Further reading[edit]

  • Nagase T, Kikuno R, Hattori A, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970. 
  • Hadano S, Hand CK, Osuga H, et al. (2001). "A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.". Nat. Genet. 29 (2): 166–73. doi:10.1038/ng1001-166. PMID 11586298. 
  • Salazar MA, Kwiatkowski AV, Pellegrini L, et al. (2004). "Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.". J. Biol. Chem. 278 (49): 49031–43. doi:10.1074/jbc.M308104200. PMID 14506234. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935. 
  • Krause M, Leslie JD, Stewart M, et al. (2004). "Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics.". Dev. Cell 7 (4): 571–83. doi:10.1016/j.devcel.2004.07.024. PMID 15469845. 
  • Dahl E, Sadr-Nabavi A, Klopocki E, et al. (2005). "Systematic identification and molecular characterization of genes differentially expressed in breast and ovarian cancer.". J. Pathol. 205 (1): 21–8. doi:10.1002/path.1687. PMID 15586368. 
  • Eppert K, Wunder JS, Aneliunas V, et al. (2005). "Altered expression and deletion of RMO1 in osteosarcoma.". Int. J. Cancer 114 (5): 738–46. doi:10.1002/ijc.20786. PMID 15609301. 
  • Jenzora A, Behrendt B, Small JV, et al. (2005). "PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins.". FEBS Lett. 579 (2): 455–63. doi:10.1016/j.febslet.2004.10.110. PMID 15642358. 
  • Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.