RAPH1

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Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols RAPH1 ; ALS2CR18; ALS2CR9; LPD; PREL-2; PREL2; RMO1; RalGDS/AF-6
External IDs OMIM609035 MGI1924550 HomoloGene71030 GeneCards: RAPH1 Gene
Orthologs
Species Human Mouse
Entrez 65059 77300
Ensembl ENSG00000173166 ENSMUSG00000026014
UniProt Q70E73 F2Z3U3
RefSeq (mRNA) NM_025252 NM_001045513
RefSeq (protein) NP_976241 NP_001038978
Location (UCSC) Chr 2:
204.26 – 204.4 Mb
Chr 1:
60.48 – 60.57 Mb
PubMed search [1] [2]

Ras-associated and pleckstrin homology domains-containing protein 1 is a protein that in humans is encoded by the RAPH1 gene.[1]


References[edit]

Further reading[edit]

  • Nagase T, Kikuno R, Hattori A et al. (2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970. 
  • Hadano S, Hand CK, Osuga H et al. (2001). "A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.". Nat. Genet. 29 (2): 166–73. doi:10.1038/ng1001-166. PMID 11586298. 
  • Salazar MA, Kwiatkowski AV, Pellegrini L et al. (2004). "Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.". J. Biol. Chem. 278 (49): 49031–43. doi:10.1074/jbc.M308104200. PMID 14506234. 
  • Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Beausoleil SA, Jedrychowski M, Schwartz D et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935. 
  • Krause M, Leslie JD, Stewart M et al. (2004). "Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics.". Dev. Cell 7 (4): 571–83. doi:10.1016/j.devcel.2004.07.024. PMID 15469845. 
  • Dahl E, Sadr-Nabavi A, Klopocki E et al. (2005). "Systematic identification and molecular characterization of genes differentially expressed in breast and ovarian cancer.". J. Pathol. 205 (1): 21–8. doi:10.1002/path.1687. PMID 15586368. 
  • Eppert K, Wunder JS, Aneliunas V et al. (2005). "Altered expression and deletion of RMO1 in osteosarcoma.". Int. J. Cancer 114 (5): 738–46. doi:10.1002/ijc.20786. PMID 15609301. 
  • Jenzora A, Behrendt B, Small JV et al. (2005). "PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins.". FEBS Lett. 579 (2): 455–63. doi:10.1016/j.febslet.2004.10.110. PMID 15642358. 
  • Hillier LW, Graves TA, Fulton RS et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.