SLC35C2

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Solute carrier family 35, member C2
Identifiers
Symbols SLC35C2 ; BA394O2.1; C20orf5; CGI-15; OVCOV1
External IDs MGI2385166 HomoloGene6581 GeneCards: SLC35C2 Gene
RNA expression pattern
PBB GE SLC35C2 219447 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 51006 228875
Ensembl ENSG00000080189 ENSMUSG00000017664
UniProt Q9NQQ7 Q8VCX2
RefSeq (mRNA) NM_015945 NM_001252573
RefSeq (protein) NP_057029 NP_001239502
Location (UCSC) Chr 20:
44.98 – 44.99 Mb
Chr 2:
165.28 – 165.29 Mb
PubMed search [1] [2]

Solute carrier family 35 member C2 is a protein that in humans is encoded by the SLC35C2 gene.[1][2][3]

Oxygenation levels play an important role in the regulation of cellular invasiveness which occurs during early implantation when the trophoblast cells invade the uterus as well as during tumour progression and metastasis. This gene, which is regulated by oxygen tension, is induced in hypoxic trophoblast cells and is overexpressed in ovarian cancer. Two protein isoforms are encoded by transcript variants of this gene.[3]

References[edit]

  1. ^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093. 
  2. ^ Fossey SC, Mychaleckyj JC, Pendleton JK, Snyder JR, Bensen JT, Hirakawa S, Rich SS, Freedman BI, Bowden DW (Sep 2001). "A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20". Genomics 76 (1-3): 45–57. doi:10.1006/geno.2001.6584. PMID 11549316. 
  3. ^ a b "Entrez Gene: SLC35C2 solute carrier family 35, member C2". 

Further reading[edit]