SLC38A1

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Solute carrier family 38, member 1
Identifiers
Symbols SLC38A1 ; ATA1; NAT2; SAT1; SNAT1
External IDs OMIM608490 MGI2145895 HomoloGene12745 GeneCards: SLC38A1 Gene
RNA expression pattern
PBB GE SLC38A1 218237 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 81539 105727
Ensembl ENSG00000111371 ENSMUSG00000023169
UniProt Q9H2H9 Q8K2P7
RefSeq (mRNA) NM_001077484 NM_001166456
RefSeq (protein) NP_001070952 NP_001159928
Location (UCSC) Chr 12:
46.58 – 46.66 Mb
Chr 15:
96.57 – 96.64 Mb
PubMed search [1] [2]

Sodium-coupled neutral amino acid transporter 1 is a protein that in humans is encoded by the SLC38A1 gene.[1][2]

Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001).[supplied by OMIM][2]

References[edit]

  1. ^ Wang H, Huang W, Sugawara M, Devoe LD, Leibach FH, Prasad PD, Ganapathy V (Sep 2000). "Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta". Biochem Biophys Res Commun 273 (3): 1175–9. doi:10.1006/bbrc.2000.3061. PMID 10891391. 
  2. ^ a b "Entrez Gene: SLC38A1 solute carrier family 38, member 1". 

Further reading[edit]