Talk:Sublingual immunotherapy

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Current Literature[edit]

The article may be improved by providing references for the safety and efficacy of SLIT and clarifying the mechanism.

I would like to propose reworking the lead paragraph as:

Sublingual Immunotherapy is method of allergy treatment that uses an allergen solution given under the tongue, which over the course of treatment, reduces sensitivity to allergens. Sublingual immunotherapy, or SLIT, has a very good safety profile [1] and is given at home in adults and children.

James Thompson 16:05, 12 November 2006 (UTC)[reply]

The lone case of anaphylaxis should be moved to the safety section and placed in context of current safety literature (a billion doses, no life threatening reactions). Gidaro (2005) or Rodriguez-Perez (2008) would be a start. The Philadelphia case cited by Dunsky occurred when a physician, new to SLIT used high doses were used in a very allergic patient, new to SLIT, who called her physicians office on two previous days describing progressive reaction to high dose drops and was reassured by the nurse that SLIT was safe ( Dunsky being the first case report of anaphylaxis). While a rare case it is an even better example of how to get into dutch.

The current literature of the extent of SLIT use, for inhalents, contact allergies and foods might make a better introduction the article. The prevention of the development of asthma would be even better.

It would be helpful if someone from the joint committee of the College or the Academy could provide a comment on the CPT code towards the end of the article since this is important but not very interesting.

James Thompson (talk) 10:55, 8 October 2008 (UTC)[reply]

Allerdrops?[edit]

I'm not sure it's proper to have a link to a product sale's website. I'm not sure the way that works here. —Preceding unsigned comment added by 24.68.234.124 (talk) 18:49, 2 November 2007 (UTC)[reply]

Quackery[edit]

Read this article carefully. It is misleading and chocked full of falsehoods. SLIT, Metabolife, chiropracty, Wikipedia is in danger of becoming a front for shills. —Preceding unsigned comment added by Curtius Maximus (talkcontribs) 17:51, 19 November 2007 (UTC)[reply]

Falsehoods such as? --Una Smith (talk) 15:28, 20 January 2008 (UTC)[reply]

DAB page[edit]

Text removed from the SLIT disambiguation page. --Una Smith (talk) 15:28, 20 January 2008 (UTC)[reply]

  • in health, SLIT is also an acronym for sublingual immunotherapy. You can find articles about it on about.comIt has been used in Europe over 10 years and is safe for young children, but has just recently been introduced in the USA. An alternative to allergy shots, the drops are easy to administer and can be done at home.
Some interesting articles about Sublingual Immunotherapy

This page needs some improvement on safety, mechanisms, current studies... to bring it up to Wikipedia standards. It may be best to keep commercial references out. SLIT has been validated in more than 40 double blind placebo controlled studies and three meta analyses. More than half the immunotherapy in Europe is SLIT. Because it represents a departure from traditional injection therapy, controversy and difference of opinion are expected. Please reference your edits, avoid personal opinion outside the discussion forum and don't take it personally if you segment undergoes a major edit.--James Thompson (talk) 04:36, 29 February 2008 (UTC)[reply]

Wow, what a mess[edit]

It's hard to find medical literature that is so lopsidedly utopian today as this article, and its sister over at Allergen immunotherapy. I added a POV-check, and I'll leave it at that. I imagine huge budgets at mammoth companies trying to "taint the jury" to hasten approval in the US. Merit speaks louder than hype. I further suggest that the "low importance" tag on this talk page be revisited; is its purpose to evade scrutiny? 64.85.169.79 (talk) 00:42, 28 August 2013 (UTC)[reply]

Merged and working to address. Doc James (talk · contribs · email) 07:38, 17 June 2015 (UTC)[reply]
  1. ^ Gidaro G. The safety of sublingual-swallow immunotherapy: an analysis of published studies. Clin Exp Allergy 35;565-571.