Topterone

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Topterone
Names
IUPAC name
(8R,9S,10R,13S,14S,17S)-17-Hydroxy-10,13-dimethyl-17-propyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Identifiers
3D model (JSmol)
ECHA InfoCard 100.056.638 Edit this at Wikidata
  • InChI=1S/C22H34O2/c1-4-10-22(24)13-9-19-17-6-5-15-14-16(23)7-11-20(15,2)18(17)8-12-21(19,22)3/h14,17-19,24H,4-13H2,1-3H3/t17-,18+,19+,20+,21+,22+/m1/s1
    Key: LZSOOHLAZHOTHJ-GUCLMQHLSA-N
  • CCC[C@@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
Properties
C22H34O2
Molar mass 330.512 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Topterone is an antiandrogen.[1]

References

  1. ^ Ferrari, RA; Chakrabarty, K; Creange, JE; Beyler, AL; Potts, OG; Schane, HP (1980). "Endocrine profile of topterone, a topical antiandrogen, in three species of laboratory animals". Methods and findings in experimental and clinical pharmacology. 2 (2): 65–9. PMID 7339330.


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