The variome is the whole set of genetic variations found in populations of species that have gone through a relatively short evolution change. For example, among humans, about 1 in every 1,200 nucleotide bases differ. However, as the human species diverged only 10,000[verification needed] years ago, this variation rate is comparatively small. In practice, the variome can be the sum of the single nucleotide polymorphisms (SNPs) of the population. Variomics is the study of variome and a branch of bioinformatics.
There are a number of international project studying the human variome, including the International HapMap Project and the Human Variome Project (HVP). The HapMap Project aims to identify and catalog genetic similarities and differences among humans. The HVP aims to collect data on all human genetic variation.
- Vizzini, Casimiro (March 19, 2015). "The Human Variome Project: Global Coordination in Data Sharing". Science & Diplomacy 4 (1).
- Variome.net: Variome information portal site.
- Human Variome Project
- "Human Variome Project Set to Launch", May 12, 2006
- What is the Human Variome Project?
- Ring H, Kwok P, Cotton R (2006). "Human Variome Project: an international collaboration to catalogue human genetic variation.". Pharmacogenomics 7 (7): 969–72. doi:10.2217/14622418.104.22.1689. PMID 17054407.