Zieve's syndrome

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Zieve's syndrome
Classification and external resources
ICD-10 K70.0
ICD-9 571.1

Zieve's syndrome is an acute metabolic condition that can occur during withdrawal from prolonged alcohol abuse. It is defined by hemolytic anemia, hyperlipoproteinaemia (excessive blood lipoprotein), jaundice, and abdominal pain.[1] The underlying cause is liver delipidization. This is distinct from alcoholic hepatitis which, however, may present simultaneously or develop later.

[edit] History

Zieve's syndrome was initially described in 1958.[2] Dr Leslie Zieve described patients with a combination of alcoholic liver disease, hemolytic anemia and hypertriglyceridemia.

[edit] References

  1. ^ Mehta, AB; N McIntyre (2004). Oxford Textbook of Clinical Hepatology. Oxford University Press. pp. 1786–1787. ISBN 0-19-262515-2. 
  2. ^ Zieve, L (March 1958). "Jaundice, hyperlipemia and hemolytic anemia: a heretofore unrecognized syndrome associated with alcoholic fatty liver and cirrhosis". Annals of Internal Medicine 48 (3): 471–476. PMID 13521581. 


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