Survival of motor neuron: Difference between revisions
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'''Survival of motor neuron''' is a protein associated with [[spinal muscular atrophy]]. |
'''Survival of motor neuron''' is a protein associated with [[spinal muscular atrophy]]. |
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A 2004 study using [[high-throughput screening]] found [[indoprofen]] to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for [[spinal muscular atrophy|spinal muscular atrophies]].<ref>{{cite journal |author=Lunn MR, Root DE, Martino AM, ''et al'' |title=Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism |journal=Chem Biol |volume=11 |issue=11 |pages=1489–93 |year=2004 |pmid=15555999 |doi=10.1016/j.chembiol.2004.08.024}}</ref> |
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==See also== |
==See also== |
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* [[motor neuron]] |
* [[motor neuron]] |
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==References== |
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{{Reflist}} |
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==External links== |
==External links== |
Revision as of 23:04, 6 October 2007
survival of motor neuron 1, telomeric | |||||||
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Identifiers | |||||||
Symbol | SMN1 | ||||||
Alt. symbols | SMA@, SMA | ||||||
NCBI gene | 6606 | ||||||
HGNC | 11117 | ||||||
OMIM | 600354 | ||||||
RefSeq | NM_000344 | ||||||
UniProt | Q16637 | ||||||
Other data | |||||||
Locus | Chr. 5 q13 | ||||||
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survival of motor neuron 2, centromeric | |||||||
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Identifiers | |||||||
Symbol | SMN2 | ||||||
NCBI gene | 6607 | ||||||
HGNC | 11118 | ||||||
OMIM | 601627 | ||||||
RefSeq | NM_017411 | ||||||
UniProt | Q16637 | ||||||
Other data | |||||||
Locus | Chr. 5 q13 | ||||||
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Survival of motor neuron is a protein associated with spinal muscular atrophy.
A 2004 study using high-throughput screening found indoprofen to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for spinal muscular atrophies.[1]
See also
References
- ^ Lunn MR, Root DE, Martino AM; et al. (2004). "Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism". Chem Biol. 11 (11): 1489–93. doi:10.1016/j.chembiol.2004.08.024. PMID 15555999.
{{cite journal}}
: Explicit use of et al. in:|author=
(help)CS1 maint: multiple names: authors list (link)
External links
- SMN+protein+(spinal+muscular+atrophy) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)