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<ref>Teif V.B., Bohinc K. (2010) Condensed DNA: condensing the concepts. ''Progr. Biophys. Mol. Biol.'' http://dx.doi.org/10.1016/j.pbiomolbio.2010.07.002</ref>


== External links ==
== External links ==

Revision as of 15:37, 5 August 2010

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DNA condensation refers to the process of compacting DNA molecules in vitro or in vivo. Mechanistic details of DNA packing are essential for its functioning in the process of gene regulation in living systems. Condensed DNA often has surprising properties, which one would not predict from classical concepts of dilute solutions. Therefore DNA condensation in vitro serves as a model system for many processes of physics, biochemistry and biology. In addition, DNA condensation has many potential applications in medicine and biotechnology.

The concept of DNA condensation

DNA condensation in viruses

DNA condensation in bacteria

DNA condensation in eukaryotes

DNA condensation in vitro

Experimental methods

Condensing agents

Morphologies of condensed DNA

Reentrant DNA condensation

Physics of DNA condensation

Coil-globule transition

Hydration forces

Counterion condensation

Counterion correlations

Counterion bridges

DNA charge reversal

DNA-DNA recognition

Computer simulations

Lattice models for chromatin

DNA condensation in the context of gene regulation

Non-enzymatic reaction rates

Enzymatic reactions rates

Condensation and origin of life

Epigenetic gene regulation

Applications of DNA condensation in medicine and biotechnology

References