Mucous membrane pemphigoid: Difference between revisions
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#REDIRECT [[Mucous membrane pemphigoid]] |
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{{DiseaseDisorder infobox | |
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Name = Pemphigoid | |
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ICD10 = L12 | |
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ICD9 = {{ICD9|694}} | |
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}} |
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'''[[Mucous membrane]] pemphigoid''', also known as '''cicatricial pemphigoid''', is an [[autoimmune]] reaction that occurs at the level of the [[basement membrane]]. Commonly affects [[gingiva]]. It is a desquamating/blistering disease in which the [[epithelium]] "unzips" from the underlying connective tissue, allowing fluid to gather that subsequently manifest as [[bullae]], or blisters. |
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[[Antibodies]] (IgG) precipitates complement (C3) in the lamina lucida of the BM. |
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Circulating auto-antibodies to BP-1 antigen (located in hemidesmosome). 50% have BP-2. |
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Positive [[Nikolsky sign]]. |
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IgG, C3 deposition at BM creating smooth line in immunoflourescent analysis. |
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==See also== |
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* [[Bullous pemphigoid]] |
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* [[Gestational pemphigoid]] |
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{{med-sign-stub}} |
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====Links==== |
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*[http://www.antibodypatterns.com/basementmembody.php Pemphigoid antibody] |
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*[http://health.groups.yahoo.com/group/PemGest/ Gestational Pemphigoid Support Group] |
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[[Category:Oral pathology]] |
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Revision as of 19:06, 23 May 2007
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