Talk:Fibrodysplasia ossificans progressiva

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Statistics

This site says 2,500 have been reported (1 in 2,000,000) to date. The most recent date is April 23, 2006.

http://www.usbjd.org/projects/project_op.cfm?dirID=142

Stovetopcookies 08:35, 16 May 2006 (UTC)

Qwantz

This disease was features in today's Qwantz would it be appropriate to create a Popular Culture section and mention it?

No. I came here because of the mention in Qwantz as well, but I don't think that nearly relevantNjerseyguy 20:20, 14 January 2007 (UTC).

Myositis ossificans

The article on myositis ossificans says that the ossification in the progressiva type of myositis ossificans (which this article refers to as fibrodysplasia ossificans progressiva) does not require injury, and develops in a predictable pattern, which seems to contradict this article. Can anyone help clear this up? Dancter 22:55, 9 June 2006 (UTC)

From what I remember from a friend that has FOP is that ossification can both occur because of injury, but injury does not always result in ossification and can also happen without an apparent cause. It also seems to vary somewhat from case to case with ossification occurring at vary different rates from person to person. Lonjers 01:24, 22 March 2007 (UTC)

My concern is that terminology may be used imprecisely, as it doesn't seem that the distinction between FOP and nonhereditary myositis ossificans is made clear among the two articles. I've tagged both with {{contradict-other}} tags to draw a little more attention to this. Dancter 04:44, 22 June 2007 (UTC)

Contradictory info from Discovery Health

Note that the info from Discovery disagrees with the 'Statistics' above. Until someone finds a published source, please stop reverting unconfirmable information you saw on cable. Cable show are not good sources for an encyclopedia. —The preceding unsigned comment was added by Lord Kelvin (talk • contribs) 01:17, 22 June 2006 (UTC)

In the study by Gannon (entitled "Mast Cell involvment in fibrodysplasia ossificans progressiva") formation of lesions in this disease are linked to activation of inflammitory mast cells. This means any injury resulting in inflammation and therefore activation of mast cells can trigger the formation of bone. This disease is not however caused by injury and has usually been found to follow a classical endochondral ossification pathway found in developing embryo. For more info read the article "Transgenic Mice Overexpressing BMP4 Develop a Fibrodysplasia Ossificans Progressiva-Like Phenotype" by Lixin Kan. —Preceding unsigned comment added by 134.50.25.59 (talk) 23:46, 26 September 2007 (UTC)

misspelling of title

i have seen this spelled fibrodysplasia ossificans progessiva,

progessiva instead of progressiva. can anyone verify this?

Jbpanther20 00:00, 29 August 2006 (UTC)jbpanther20

Sounds to me like it's simply a misspelling.WizardofOskemen 22:24, 19 October 2006 (UTC)

Yea, "progressiva" refers to the progressive nature of the disease. See the International Fibrodysplasia Ossificans progressiva Association webpage. Njerseyguy 20:23, 14 January 2007 (UTC)

Excellent picture.

A haunting picture of Harry Eastwick appears side by side with his skeleton (post mortem) is available here (google image frame. The original page is here. Anyone with some time might want to add the photo or at least link to it. Njerseyguy

On a side note, I can't spell worth a damn Njerseyguy 20:27, 14 January 2007 (UTC)

Spelling corrected and noted that the first shot is not a cadever

70.123.129.246 (talk) 22:34, 20 January 2008 (UTC)Steve Eichner70.123.129.246 (talk) 22:34, 20 January 2008 (UTC)

Mr. Eastlack's Case

The "cases" section of this article starts talking about someone named "Mr. Eastlack." The second paragraph starts referring to someone who can only move their lips, but never says their name. The third paragraph mentions a "Mr. Eastlack." Is Mr. Eastlack the person from the second paragraph? Does Mr. Eastlack have a full name? Is he worth mentioning? Please, REWRITE THIS SECTION.

(No, I'm not a real doctor)

Dr. Mordecai 01:48, 23 March 2007 (UTC)

Documentary on FOP

Discovery Health Channel ran a documentary on FOP a few years ago, titled "Skeleton Key". It opened with video of Eastlack's deformed skeleton.