Talk:Graves' disease

Basedow's disease

Just for reference, Graves' disease is also called Basedow's disease in Japan. Cyborg Ninja 03:42, 3 June 2007 (UTC)

Immune Therapy

Has any work been done on immune therapy treatments for graves disease? --74.99.4.177 21:49, 3 April 2007 (UTC)

I haven't heard of any immune therapy treatments being used for Graves' disease. Are you talking about like using a drug to suppress the immune system? I think that the risks from those drugs make them a bad choice when there are two better options available, and that's why it's rarely if ever used. Cyborg Ninja 03:42, 3 June 2007 (UTC)

Reference check

The reference to Heino needs checking. As far as I know he wears glasses because he is an albino. If he suffers from GB disease as well so be it, but it's news to me...

I've tidied up some grammar, although mine isn't great, and added a little on alternative names for the eye problem, and headache as a symptom, as it is a common presenting symptom (patients who are thyrotoxic exhibit symptoms of poisoning, as the name suggests, which include headache, nausea and bloodshot eyes , very similar to waking up each morning with a bad hangover but without the need for alcohol).

I don't have a reference to hand, but I'm fairy sure the 4:1 female to male ratio is too low. At least one reference claims 20 in a 1000 women, and 1 in a thousand men as occurence, but also notes that the disease appears to be becoming more common (with no clear evidence whether this is due to better diagnosis, or an increase in frequency).

Not sure on the policy of linking to other sites, but members of the Chicago thyroid center, and other researchers extensively published in the peer reviewed medical literature maintain an encyclopedic reference on thyroid disorders at http://www.thyroidmanager.org/ which might be of use to those researching the topic.

There is some controversy on the use of Iodine 131 in treating the disorder, as it is linked to an increase in the occurence of eye problems. However since no reference to treament is in the original page I'm not sure if a discussion of such is appropriate there. The hyperthyroidism is usually adequately treated with antithyroid drugs or a partial thyroidectomy. The eye problems may be treated with steroids, eye drops, and ultimately surgery or orbital radiation treatments, although recent studies suggest the orbital radiation treatment may not be as effective as once thought.

References

The references had been shamelessly copy&pasted from Whonamedit.com. I've reformatted them. We need some discussion on whether all those old references need to be mentioned, while there are no references to clinical or pathological reviews! Your opinions please. JFW | T@lk 11:41, 2 Jan 2005 (UTC)

Thank you anonymous editor, but please work on your style. Bulletted lists and lots of capitals do not make it prettier.... JFW | T@lk 09:58, 6 Feb 2005 (UTC)

Q. Is cardiac failure rare? if so, can you say so, so as not to alarm suffers using this page to find out what they've got. thanks

A. Yes, cardiac failure is rare, usually occurring in post-thyroidectomy patients due to a temporary increase in thyroid hormones (Thyroid Storm) brought on by surgery. Thyroid Storm is a rare but serious complication of Graves' Disease, heart failure is a complication of thyroid storm (otherwise known as thyrotoxicosis). The likelihood of developing thyrotoxicosis is low because, most patients undergo Thyroid Hormone Suppressant therapies prior to surgery.

Please, understand that Graves' Disease is a very serious condition. The information provided is intended to inform, not to scare. It is estimated that 13 million people in the United States alone have undiagnosed Hyperthyroidism. Articles like this help to increase public awareness of serious autoimmune diseases like Graves', Hashimos Thyroiditis, Hypothyroidism, and etc...

The following is an excerpt from my paper, Graves' Disease, A cause for concern which was inspired by my mother whom, I almost lost to Graves' Disease 3 years ago.

"It should be noted, Thyroid Storm is deadly if left untreated. Its symptoms include, Tachycardia (abnormally rapid heart rate), Diaphoresis (profuse sweating), and Dehydration secondary to GI losses (commonly referred to as diarrhea). Patients experiencing Thyroid Storm may also exhibit: Warm, moist skin, Widened pulse pressure, Congestive heart failure (may be a high output failure), Thyromegaly (meaning goiter or abnormally enlarged thyroid gland), Exophthalmos {protrusion of the eyeball from the socket), Shock, Atrial fibrillation. There are no clinical tests to determine Thyroid Storm as a cause so, “In the emergency department, thyroid storm often must be recognized and treated on clinical grounds, because laboratory confirmation of the disease cannot be obtained in a timely manner.” Those who experience these symptoms should seek immediate medical care."

From: Graves' Disease, A cause for concern By: Brandie A. Plunkett Contact: brandieann@clearwire.net

Reference: http://www.emedicine.com/emerg/topic269.htm

Suggestions for "noted sufferers

Suggestions for "noted suffers" for a more varied selection.

• Yolanda Gail Devers -- US Olympic Athlete -- ref Wikipedia and gaildevers.com biography
• Janica Kostelic -- Croatian Olympic, and World class, skier -- ref http://www.janica.hr (note reference says only thyroid problem).
• Marty Feldman -- British Actor and Comedian -- ref Wikipedia (note reference says only thyroid problem).

Move/Rename from Graves-Basedow disease to Graves disease

The following discussion is an archived debate of the proposal. Please do not modify it. Subsequent comments should be made in a new section on the talk page. No further edits should be made to this section.

The result of the debate was PAGE MOVED per discussion below. There was a history at Graves disease, including one edit with content that got merged into the main article, so rather than just deleting the page in the way of the move, I swapped their histories, so the history previously at Graves disease can now be found at Graves-Basedow disease, and vice-versa. -GTBacchus^(talk) 11:06, 20 January 2007 (UTC)

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I'm more familiar with this entity being known as Graves disease rather than Graves-Basedow disease. Comments? Andrew73 21:16, 7 January 2007 (UTC)

(copied and indentation reformated from Wikipedia talk:WikiProject Clinical medicine): David Ruben ^Talk 03:59, 14 January 2007 (UTC)

• Rename - Of the standard disease sources given in the Template:Infobox Disease: ICD10's E05.0, OMIM and MedlinePlus links refer only to "Graves Disease". eMedicine titles its article as "Graves Disease" and under 'Synonyms and related keywords:' lists "diffuse toxic goiter, thyrotoxicosis, hyperthyroidism" before mentioning Basedow's disease. Finally Diseases Database link is headed "Graves' disease aka/or Basedow's disease".

eMedicine's Goiter, Diffuse Toxic article explains that "This condition was first described by the English physician Caleb H. Parry (1755-1822). The disorder is known as Graves disease (after Robert J. Graves) in the English-speaking world and as Basedow disease (after Karl A. von Basedow) in the rest of Europe.". So given this is English-language wikipedia, I suspect the article should follow the term used in "the English-speaking world", although mention of non-English speaking world's term in the article's introduction would be appropriate. David Ruben ^Talk 03:16, 8 January 2007 (UTC)

• Here in non-English speaking the Netherlands located somewhere in the rest of Europe, I have never heard of Basedow disease :-) --WS 20:18, 11 January 2007 (UTC)
• Support per nom. There was a study in the papers a few weeks back and it was listed as Graves Disease and it is the only name that I have, personally, heard associated with it. 205.157.110.11 14:49, 14 January 2007 (UTC)

The above discussion is preserved as an archive of the debate. Please do not modify it. Subsequent comments should be made in a new section on this talk page. No further edits should be made to this section.

Etiology

This section still needs some work. Wwallacee 21:22, 21 February 2007 (UTC)

Bugleweed

Is the bugleweed recommendation suitable encyclopedia material?-Wetman 05:29, 11 October 2007 (UTC)

I'd have thought Bugleweed and Lemon balm would qualify for a mention as they are recognized herbal treatments. I'm not aware of any evidence that they work, and they certainly present the risk people might try them instead of therapies which are proven to be effective, but their (mis-?)use in this condition is a matter of fact not opinion.

There is no reason that it should be a recommendation, without evidence they work as well or better than the current best drug (Methimazole/Carbimazole), which given my experience of people who tried the herbal route is unlikely to be forthcoming without significant advances in the herbal treatments. —Preceding unsigned comment added by 84.45.158.52 (talk) 12:07, 15 December 2007 (UTC)

Graves disease or Graves' disease?

• Discussion at Wikipedia talk:MED#Eponymous disease possessive naming. Anthony Appleyard (talk) 10:47, 11 February 2008 (UTC)
  • Currently archived at Wikipedia talk:WikiProject Medicine/Archive 6#Eponymous disease possessive naming.
    Bistromaths (talk) 16:24, 2 January 2009 (UTC)

No treatment?

Should the section titled "No treatment" be "Natural history" instead? 192.234.106.2 (talk) 19:16, 30 April 2008 (UTC)