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Trudeau Institute is an independent, not-for-profit Biomedical Research Center, whose scientific mission is to make breakthrough discoveries that lead to improved human health. With an annual operating budget of over $16 million in research grant support, Trudeau’s scientists work to discover the basic rules governing how the body’s natural defense system, immunity, attacks influenza, plague, Tuberculosis, Toxoplasmosis and tumors of the lung as well as how an overactive immune response, autoimmunity, results in asthma, arthritis and allergies.

Trudeau Institute was originally founded in 1884 as a tuberculosis sanitarium and then in 1964 as a research institute. Located in the northern New York Village of Saranac Lake, Trudeau is among the area’s largest employers and fosters a highly collaborative research environment where multiple investigative teams examine distinct facets of immune response to infectious disease, particularly those pathogens that infect via the lung and respiratory tract. The studies are done efficiently due to use of shared resources, shared expertise and shared information. The many kinds of answers obtained often synergize to allow new insight into basic mechanisms of immunity to respiratory pathogens.

The Institute is home to thirteen world-class research teams, who all study some aspect of infection and immunity, but across a variety of different pathogens. Their studies focus not only on immune responses to major infectious diseases, such as influenza and tuberculosis, but also on the role of the immune system in cancer, autoimmunity, and aging.

Each research team, comprised of a Principal Investigator, postdoctoral fellows and highly trained technical staff, receive average annual grant support of just over $1 million, based largely upon success in earning highly competitive federal grants, principally from the National Institutes of Health. The Institute employes over 60 Ph.D.’s from 12 countries. While many universities and private research institutions have several groups dedicated to immunology or infectious disease research, having such a large interactive group devoted to studying immunity is unique and promotes rapid progress.

Using state-of-the-art experimental methodologies and mouse models, Trudeau researchers at the 25 acre campus utilize core facilities which include our Animal, Flow Cytometry, Molecular, Imaging & Microscopy cores as well as BSL2 and BSL3 containment laboratories. Because all the groups use each facility extensively, and because the groups often collaborate in their research, the cores are used efficiently and the many projects synergize nicely.

During the Fall of 2009, an additional 10,000 square feet of laboratory and support space will be commissioned. The new space will provide state-of-the-art facilities for the Institute’s research in tuberculosis, pandemic influenza and other infectious diseases. The new wing is named in honor of former state senator Ronald B. Stafford, who also served on the Trudeau Institute’s board of trustees.

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 [[Image:Trudeau Institute Campus from Saranac Lake.jpg|thumb|Campus of the Trudeau Institute from [[Lower Saranac Lake]].]]
 [[Image:Saranac Lake - Trudeau Lab.jpg|thumb|Saranac Laboratory, precursor to the Trudeau Institute. Presently the home of [[Historic Saranac Lake]], a local nonprofit, historic preservation organization]]
-The '''Trudeau Institute''', located in [[Saranac Lake, New York]], was founded by Dr. [[Edward Livingston Trudeau]] in 1884 as a [[tuberculosis]] treatment and research facility.
+Trudeau Institute is an independent, not-for-profit Biomedical Research Center, whose scientific mission is to make breakthrough discoveries that lead to improved human health.  With an annual operating budget of over $16 million in research grant support, Trudeau’s scientists work to discover the basic rules governing how the body’s natural defense system, immunity, attacks influenza, plague, Tuberculosis, Toxoplasmosis and tumors of the lung as well as how an overactive immune response, autoimmunity, results in asthma, arthritis and allergies.
-Trudeau trained as a doctor after the death of his elder brother due to tuberculosis. He himself was diagnosed with the disease in 1873. Following conventional thinking of the times, his physicians and friends urged a change of climate.  He went to live in the [[Adirondack Mountains]], initially at [[Paul Smith's Hotel]], spending as much time as possible in the open; he subsequently regained his health. In 1876 he moved to Saranac Lake and established a medical practice among the sportsmen, guides and lumber camps of the region.
+Trudeau Institute was originally founded in 1884 as a tuberculosis sanitarium and then in 1964 as a research institute.  Located in the northern New York Village of Saranac Lake, Trudeau is among the area’s largest employers and fosters a highly collaborative research environment where multiple investigative teams examine distinct facets of immune response to infectious disease, particularly those pathogens that infect via the lung and respiratory tract.  The studies are done efficiently due to use of shared resources, shared expertise and shared information.  The many kinds of answers obtained often synergize to allow new insight into basic mechanisms of immunity to respiratory pathogens.
-In 1882, Trudeau read about [[Prussia]]n Dr. [[Hermann Brehmer]]'s success treating tuberculosis with the "rest cure" in cold, clear mountain air.  Following this example, Trudeau founded the [[Adirondack Cottage Sanitarium]], with the support of several of the wealthy businessmen he had met at Paul Smiths. In 1894, after a fire destroyed his small laboratory, Trudeau organized the '''Saranac Laboratory for the Study of Tuberculosis''', the first laboratory in the United States for the study of tuberculosis.
+The Institute is home to thirteen world-class research teams, who all study some aspect of infection and immunity, but across a variety of different pathogens. Their studies focus not only on immune responses to major infectious diseases, such as influenza and tuberculosis, but also on the role of the immune system in cancer, autoimmunity, and aging.
-As new drugs became available in the 1950s to treat the disease, the Institute was rededicated as an independent [[nonprofit]] organization committed to world-class [[medical research]].
+Each research team, comprised of a Principal Investigator, postdoctoral fellows and highly trained technical staff, receive average annual grant support of just over $1 million, based largely upon success in earning highly competitive federal grants, principally from the National Institutes of Health.  The Institute employes over 60 Ph.D.’s from 12 countries.  While many universities and private research institutions have several groups dedicated to immunology or infectious disease research, having such a large interactive group devoted to studying immunity is unique and promotes rapid progress.
+Using state-of-the-art experimental methodologies and mouse models, Trudeau researchers at the 25 acre campus utilize core facilities which include our Animal, Flow Cytometry, Molecular, Imaging & Microscopy cores as well as BSL2 and BSL3 containment laboratories.  Because all the groups use each facility extensively, and because the groups often collaborate in their research, the cores are used efficiently and the many projects synergize nicely.
+During the Fall of 2009, an additional 10,000 square feet of laboratory and support space will be commissioned. The new space will provide state-of-the-art facilities for the Institute’s research in tuberculosis, pandemic influenza and other infectious diseases. The new wing is named in honor of former state senator Ronald B. Stafford, who also served on the Trudeau Institute’s board of trustees.
-Today, the Institute carries out basic [[biomedical research]] to identify the processes used by the [[immune system]] to combat [[viruses]] like [[influenza]] and tuberculosis, [[parasite]]s, and [[cancer]], so that better vaccines and therapies can be developed for fighting the most dangerous diseases.
-The institute employs 39 full-time life-science researchers, and another 21 support staff. In 2006, it received $11.7 million in federal funding.
 ==External links==