Disodium inosinate: Difference between revisions
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[[zh:5'-肌苷酸二钠]] |
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Revision as of 08:49, 6 April 2010
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| Names | |
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| IUPAC names
Disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-
9H-purin-9-yl)tetrahydrofuran-2-yl]methyl phosphate [citation needed] | |
| Other names
Disodium 5'-inosinate
Sodium 5'-inosinate Disodium inosine 5'-monophosphate Inosine 5'-(disodium phosphate) Sodium inosinate | |
| Identifiers | |
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3D model (JSmol)
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| ECHA InfoCard | 100.022.860 |
| E number | E631 (flavour enhancer) |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C10H11N4Na2O8P | |
| Molar mass | 392.17 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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 | This article needs additional citations for verification. (February 2010) |
Disodium inosinate (E631 [1]) [clarification needed], chemical formula C10H11N2Na2O8P, is the disodium salt of inosinic acid. It is a food additive often found in instant noodles, potato chips, and a variety of other snacks. It is used as a flavor enhancer, in synergy with monosodium glutamate (also known as MSG; the sodium salt of glutamic acid) to provide the umami taste. It is mainly found in animals like pigs and fish [citation needed].
In the US, consumption of added 5'-ribonucleotides averages 4 mg per day, compared to 2 g per day of naturally occurring purines. A review of literature by an FDA committee found no evidence of carcinogenicity, teratogenicity, or adverse effects on reproduction.[2]
As it is a fairly expensive additive, it usually is not used independently of glutamic acid; if disodium inosinate is present in a list of ingredients but MSG does not appear to be, it is possible that glutamic acid is provided as part of another ingredient or is naturally occurring in another ingredient like tomatoes, Parmesan cheese or yeast extract. It is often added to foods in conjunction with disodium guanylate; the combination is known as disodium 5'-ribonucleotides.
Toxicology and safety
In 2004, the substance was removed from the food additive list by Codex Alimentarius Commission [3]
![[icon]](/wiki/File:Wiki_letter_w_cropped.svg){kind=small} | This section needs expansion. You can help by adding to it. (February 2010) |
Compendial status
| This section needs expansion. You can help by adding to it. (6 April 2010) |
See also
Notes & references
- ^ Food Standards Australia New Zealand. "Food Additives- Numerical List". Retrieved 1 December 2009.
{{cite web}}: Cite has empty unknown parameter:|coauthors=(help) - ^ DISODIUM 5'-GUANYLATE AND DISODIUM 5'-INOSINATE First draft prepared by Dr K. Ekelman and Dr K. C. Raffaele, Additives Evaluation Branch Division of Health Effects Evaluation Center for Food Safety and Applied Nutrition Food and Drug Administration, Washington, DC, USA
- ^ Codex Alimentarius Commission. "Report of the 36th Session of the Codex Committee on Food Additives and Contaminants" (PDF). Retrieved 2 December 2009.
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