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'''Methoxetamine''' or 3-MeO-2-Oxo-PCE is a chemical of the [[arylcyclohexylamine]] class. It is an [[chemical analog|analogue]] of [[ketamine]] that also contains structural features of [[eticyclidine]] and [[3-MeO-PCP]]. Like ketamine, it is thought to behave as a [[NMDA receptor antagonist]] and [[dopamine reuptake inhibitor]], though it has not been formally profiled pharmacologically. Anecdotal reports suggest a longer duration than ketamine.<ref name="Methoxetamine">[http://www.bluelight.ru/vb/showpost.php?p=9110438&postcount=18], knockando. (14 February 2011). "Methoxetamine". Bluelight.ru. Retrieved 2011-02-14.</ref> Methoxetamine differs from many other dissociative anesthetics of the arylcyclohexylamine class in that it was designed for [[grey-market]] distribution. Methoxetamine is a product of rational [[drug design]]: its N-ethyl group was chosen to increase potency, lessing the risk of [[Interstitial cystitis]] that can result from the accumulation of ketamine-like metabolites in the urinary bladder.<ref name="Interview with a ketamine chemist">[http://www.viceland.com/int/v18n2/htdocs/interview-with-ketamine-chemist-704.php?page=1], Morris, H. (11 February 2011). "Interview with a ketamine chemist: or to be more precise, an arylcyclohexylamine chemist". Vice Magazine. Retrieved 2011-02-11.</ref>
'''Methoxetamine''' or 3-MeO-2-Oxo-PCE is a chemical of the [[arylcyclohexylamine]] class. It is an [[chemical analog|analogue]] of [[ketamine]] that also contains structural features of [[eticyclidine]] and [[3-MeO-PCP]]. Like ketamine, it is thought to behave as a [[NMDA receptor antagonist]] and [[dopamine reuptake inhibitor]], though it has not been formally profiled pharmacologically. Anecdotal reports suggest a longer duration than ketamine.<ref name="Methoxetamine">[http://www.bluelight.ru/vb/showpost.php?p=9110438&postcount=18], knockando. (14 February 2011). "Methoxetamine". Bluelight.ru. Retrieved 2011-02-14.</ref> Methoxetamine differs from many other dissociative anesthetics of the arylcyclohexylamine class in that it was designed for [[grey-market]] distribution. Methoxetamine is a product of rational [[drug design]]: its N-ethyl group was chosen to increase potency, lessing the risk of [[Interstitial cystitis]] that can result from the accumulation of ketamine-like metabolites in the urinary bladder.<ref name="Interview with a ketamine chemist">[http://www.viceland.com/int/v18n2/htdocs/interview-with-ketamine-chemist-704.php?page=1], Morris, H. (11 February 2011). "Interview with a ketamine chemist: or to be more precise, an arylcyclohexylamine chemist". Vice Magazine. Retrieved 2011-02-11.</ref>

However it is worth noting that it only has a structural similarities to Ketamine and Methoxetamine is a totally different substance. This is a research chemical. Drug users should be aware that this compound is geared towards the scientific community. It is also trademarked stating "Methoxetamine is a legal Ketamine alternative for the laboratory research."<ref name="Methoxetamine™">[www.methoxetamine.co.uk/]</ref>


==See also==
==See also==

Revision as of 07:03, 8 March 2011

Methoxetamine
Clinical data
ATC code
  • None
Identifiers
  • 2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H21NO2
Molar mass231.3327 g/mol g·mol−1
3D model (JSmol)
  • O=C1CCCCC1(NCC)c2cccc(c2)OC
  (verify)

Methoxetamine or 3-MeO-2-Oxo-PCE is a chemical of the arylcyclohexylamine class. It is an analogue of ketamine that also contains structural features of eticyclidine and 3-MeO-PCP. Like ketamine, it is thought to behave as a NMDA receptor antagonist and dopamine reuptake inhibitor, though it has not been formally profiled pharmacologically. Anecdotal reports suggest a longer duration than ketamine.[1] Methoxetamine differs from many other dissociative anesthetics of the arylcyclohexylamine class in that it was designed for grey-market distribution. Methoxetamine is a product of rational drug design: its N-ethyl group was chosen to increase potency, lessing the risk of Interstitial cystitis that can result from the accumulation of ketamine-like metabolites in the urinary bladder.[2]

See also

References

  1. ^ [1], knockando. (14 February 2011). "Methoxetamine". Bluelight.ru. Retrieved 2011-02-14.
  2. ^ [2], Morris, H. (11 February 2011). "Interview with a ketamine chemist: or to be more precise, an arylcyclohexylamine chemist". Vice Magazine. Retrieved 2011-02-11.