Talk:Troponin

The following reference was inserted:

Rottbauer W, Greten T, Müller-Bardoff M, Remppis A, Zehelein J, Grünig E, Katus HA. Troponin T: a diagnostic marker for myocardial infarction and minor cardiac cell damage. Eur Heart J 1996;17:3-8.

It looks useful, but no part of the article presently refers to it. JFW | T@lk 10:44, 31 July 2006 (UTC)

Image

The new image looks somewhat amateuristic, IMHO. Anyone able to redraw it? JFW | T@lk 20:53, 17 January 2007 (UTC)

It's also fairly flawed because it implies that binding of four calcium ions is significant, when actually just one or two are regulatory, in cardiac or skeletal muscle, respectively. There is a lot of debate about the other two calciums, and they could well be replaced by magenesium in various biochemical contexts. I can redraw it, or we can perhaps duplicate an image from one of the open access journals. rmbh 02:45, 18 May 2007 (UTC)

Redrawn. Quite simplified but now much more useful, and doesn't imply (as the previous one did) that 4 Ca2+ bind in a regulatory fashion. rmbh (talk) 00:23, 1 January 2011 (UTC)

Troponin subunits

I suggest merging the 3 subunits and their descriptions into this article as a subtopic. Each article for the subunits are very short and would better contribute in this multimer complex article. Only when their descriptions are significant should they have their own link. LostLucidity (talk) 16:37, 28 January 2008 (UTC)

Troponin complex

I suggest merging with Troponin complex arcicle, while keeping Troponin test article separate. --Kender (talk) 19:35, 20 April 2010 (UTC)

Definitely keep troponin test separate from troponin. the test is itself a huge deal, very different from the biology of troponins. -Immunology2 —Preceding unsigned comment added by 171.67.129.16 (talk) 05:12, 1 May 2011 (UTC)

Heart contractile function

I've added this because I read a small article about this and didn't see it here - might be relevant for someone, someday. If anyone can extend this section, please do. — Preceding unsigned comment added by RonaldKunenborg (talk • contribs) 20:37, 21 February 2011 (UTC)

Pronunciation guide

I tried to add a pronunciation guide & its url after "Troponin is" but it created a big gap in the text. I hope an editor can add it:

http://dictionary.reference.com/browse/troponin pronounced TROH-puh-nin 24.0.113.90 (talk) 12:30, 9 May 2012 (UTC)

Likely disruption of tronopin T gene in obese humans & movement disorder

I hope an editor can integrate this info into the article bc it's highly relevant to the obesity epidemic and how lifestyle changes can affect gene function and therefore profoundly affect health:

http://well.blogs.nytimes.com/2011/05/18/the-body-weight-muscle-mismatch/ ' “It seems likely” that there are changes in troponin T activity in obese people’s muscles and that, as a result, “it really is physiologically hard for them to move,” [Dr Marden said.]' 24.0.113.90 (talk) 12:48, 9 May 2012 (UTC)