Stanol ester: Difference between revisions
m Bot: Migrating 1 interwiki links, now provided by Wikidata on d:q2127546 |
natural compound could not be "developed by a Finnish chemist"; not only one company markets stanol esters |
||
| Line 2: | Line 2: | ||
Stanol ester is often added to [[rapeseed]] oil based [[margarine]] or other foods for its health benefits. Studies have indicated that consumption of about 2 grams per day provides a reduction in LDL cholesterol of about 10%. The compound itself passes through the [[Gut (zoology)|gut]] without entering the [[blood]] stream or [[lymph]]. Its presence, however, reduces both the amount of [[cholesterol]] the body absorbs from food and the reabsorption of the cholesterol component of [[bile]]. |
Stanol ester is often added to [[rapeseed]] oil based [[margarine]] or other foods for its health benefits. Studies have indicated that consumption of about 2 grams per day provides a reduction in LDL cholesterol of about 10%. The compound itself passes through the [[Gut (zoology)|gut]] without entering the [[blood]] stream or [[lymph]]. Its presence, however, reduces both the amount of [[cholesterol]] the body absorbs from food and the reabsorption of the cholesterol component of [[bile]]. |
||
Stanol ester was developed by [[Ingmar Wester]], a [[Finland|Finnish]] chemist. It is marketed by the [[Raisio Group]] with the trade name [[Benecol]]. |
|||
[[Sterol ester]]s can also be used for the same purpose. These compounds have the same effect to LDL, but they are partially absorbed by the body. The effects of higher serum plant sterol levels are so far not completely understood. |
[[Sterol ester]]s can also be used for the same purpose. These compounds have the same effect to LDL, but they are partially absorbed by the body. The effects of higher serum plant sterol levels are so far not completely understood. |
||
Revision as of 08:24, 27 March 2013
Stanol ester is a heterogeneous group of chemical compounds known to reduce the level of low-density lipoprotein (LDL) cholesterol in blood when ingested,[1] though to a much lesser degree than prescription drugs such as statins.[2] The starting material is phytosterols from plants. These are first hydrogenated to give a plant stanol which is then esterified with a mixture of fatty acids also derived from plants. Plant stanol esters are found naturally occurring in small quantities in fruits, vegetables, nuts, seeds, cereals, legumes, and vegetable oils.
Stanol ester is often added to rapeseed oil based margarine or other foods for its health benefits. Studies have indicated that consumption of about 2 grams per day provides a reduction in LDL cholesterol of about 10%. The compound itself passes through the gut without entering the blood stream or lymph. Its presence, however, reduces both the amount of cholesterol the body absorbs from food and the reabsorption of the cholesterol component of bile.
Sterol esters can also be used for the same purpose. These compounds have the same effect to LDL, but they are partially absorbed by the body. The effects of higher serum plant sterol levels are so far not completely understood.
See also
References
- ^ Katan, MB; Grundy, SM; Jones, P; Law, M; Miettinen, T; Paoletti, R; Stresa Workshop, Participants (2003). "Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels". Mayo Clinic proceedings. Mayo Clinic. 78 (8): 965–78. doi:10.4065/78.8.965. PMID 12911045.
- ^ Doggrell, SA (2011). "Lowering LDL cholesterol with margarine containing plant stanol/sterol esters: Is it still relevant in 2011?". Complementary therapies in medicine. 19 (1): 37–46. doi:10.1016/j.ctim.2010.12.004. PMID 21296266.
External links
- American Heart Association
- American Dietetic Association
- Benecol products and research data
- Weingärtner O.; et al. (2009). "Controversial role of plant sterol esters in the management of hypercholesterolaemia". Eur Heart J. 30 (4): 404–9. doi:10.1093/eurheartj/ehn580. PMC 2642922. PMID 19158117.
{{cite journal}}: Explicit use of et al. in:|author=(help) - Weingartner, O.; Ulrich, C.; Lutjohann, D.; Ismail, K.; Schirmer, S. H.; Vanmierlo, T.; Bohm, M.; Laufs, U. (2011). "Differential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE-/- mice". Cardiovascular Research. 90 (3): 484–92. doi:10.1093/cvr/cvr020. PMC 3096304. PMID 21257611.