International Lyme and Associated Diseases Society: Difference between revisions
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The '''International Lyme And Associated Diseases Society''' (ILADS, pronounced {{IPA|/ˈaɪlædz/}}) describes itself as a nonprofit, international, multi-disciplinary medical society, dedicated to the diagnosis and appropriate treatment of Lyme and its associated diseases. ILADS promotes understanding of Lyme and its associated diseases through research and education and strongly supports physicians and other health care professionals dedicated to advancing the standard of care for Lyme and its associated diseases. The Society supports research to disprove the conventional medical opinion of the ''Infectious Disease Association of America'' that "patients who remain seronegative, despite continuing symptoms for 6-8 weeks, are unlikely to have Lyme disease."<ref name="idsa-guide">{{cite journal |author=Wormser GP, ''et al.'' |title=Clinical practice guidelines by the IDSA" |Clin Infect Dis. 2006 Nove 1;43(9):1089-134. Epub 2006 Oct 2}}</ref> and |
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The '''International Lyme And Associated Diseases Society''' (ILADS, pronounced {{IPA|/ˈaɪlædz/}}) is a [[non-profit group|non-profit]] [[interest group]] which advocates for greater acceptance of the controversial medical entity of [[chronic Lyme disease]].<ref name="forbes">{{cite news | work = [[Forbes (magazine)|Forbes]] | first = David | last = Whelan | title = Lyme, Inc. | url = http://www.forbes.com/forbes/2007/0312/096.html | date = March 12, 2007 | accessdate = July 6, 2009}}</ref> |
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the "unproven and very improbable assumption that chronic B. burgdorgeri infection can occur in the absence of antibodies against B. burgdorferi in serum." <ref name="nejm-cld">{{cite journal |author=Feder HM, Johnson BJ, O'Connell S, ''et al.'' |title=A critical appraisal of "chronic Lyme disease" |journal=N. Engl. J. Med. |volume=357 |issue=14 |pages=1422–30 |year=2007 |month=October |pmid=17914043 |doi=10.1056/NEJMra072023 |url=http://content.nejm.org/cgi/content/full/357/14/1422}}</ref> |
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Examples of false Seronegativity are extensively documented on their website, including papers published by authors of the IDSA treatment guidelines.<ref name="br-j-dermator">{{cite journal |author=Breier F, Khanakah G, Stanek G, ''et al.'' |title=Isolation and PCR typing of B afzelii from a skin lesion in a seronegative patient |Br J Dermatol. 2001 Feb;144(2):387-92}}</ref><ref name="Ann-i">{{cite journal |Dinerman H, Steere AC|title=Lyme disease associated with fibromylagia}}</ref> |
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[[Lyme_disease#Chronic_Lyme_disease_and_post-Lyme_syndrome|Controversy exists]] as to the existence of "chronic Lyme disease", with some advocating for the use of long term antibiotics for treatment of a postulated persistent infection. However, the assumption that there is a persistent infection is not supported by high quality clinical evidence, and the use of long term antibiotics is not recommended.<ref name="nejm-cld">{{cite journal |author=Feder HM, Johnson BJ, O'Connell S, ''et al.'' |title=A critical appraisal of "chronic Lyme disease" |journal=N. Engl. J. Med. |volume=357 |issue=14 |pages=1422–30 |year=2007 |month=October |pmid=17914043 |doi=10.1056/NEJMra072023 |url=http://content.nejm.org/cgi/content/full/357/14/1422}}</ref> However, patient advocacy organizations, as well as the [[Center for Science in the Public Interest]] support the ILADS position.{{cn|date=July 2013}} Major US medical authorities, including the [[Infectious Diseases Society of America]], the [[American Academy of Neurology]], and the [[National Institutes of Health]], have stated that there is no convincing evidence that ''Borrelia'' is involved in chronic Lyme disease. ILADS has questioned the generalizability and reliability of some of the trials referred to by IDSA and the reliability of the current diagnostic tests.<ref name="Stricker 2007">{{cite journal |author=Stricker RB |title=Counterpoint: long-term antibiotic therapy improves persistent symptoms associated with Lyme disease |journal=Clinical Infectious Diseases |volume=45 |issue=2 |pages=149–57 |year=2007 |month=July |pmid=17578772 |doi=10.1086/518853 |url=}}</ref> |
[[Lyme_disease#Chronic_Lyme_disease_and_post-Lyme_syndrome|Controversy exists]] as to the existence of "chronic Lyme disease", with some advocating for the use of long term antibiotics for treatment of a postulated persistent infection. However, the assumption that there is a persistent infection is not supported by high quality clinical evidence, and the use of long term antibiotics is not recommended.<ref name="nejm-cld">{{cite journal |author=Feder HM, Johnson BJ, O'Connell S, ''et al.'' |title=A critical appraisal of "chronic Lyme disease" |journal=N. Engl. J. Med. |volume=357 |issue=14 |pages=1422–30 |year=2007 |month=October |pmid=17914043 |doi=10.1056/NEJMra072023 |url=http://content.nejm.org/cgi/content/full/357/14/1422}}</ref> However, patient advocacy organizations, as well as the [[Center for Science in the Public Interest]] support the ILADS position.{{cn|date=July 2013}} Major US medical authorities, including the [[Infectious Diseases Society of America]], the [[American Academy of Neurology]], and the [[National Institutes of Health]], have stated that there is no convincing evidence that ''Borrelia'' is involved in chronic Lyme disease. ILADS has questioned the generalizability and reliability of some of the trials referred to by IDSA and the reliability of the current diagnostic tests.<ref name="Stricker 2007">{{cite journal |author=Stricker RB |title=Counterpoint: long-term antibiotic therapy improves persistent symptoms associated with Lyme disease |journal=Clinical Infectious Diseases |volume=45 |issue=2 |pages=149–57 |year=2007 |month=July |pmid=17578772 |doi=10.1086/518853 |url=}}</ref> |
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Revision as of 09:05, 27 December 2013
The International Lyme And Associated Diseases Society (ILADS, pronounced /ˈaɪlædz/) describes itself as a nonprofit, international, multi-disciplinary medical society, dedicated to the diagnosis and appropriate treatment of Lyme and its associated diseases. ILADS promotes understanding of Lyme and its associated diseases through research and education and strongly supports physicians and other health care professionals dedicated to advancing the standard of care for Lyme and its associated diseases. The Society supports research to disprove the conventional medical opinion of the Infectious Disease Association of America that "patients who remain seronegative, despite continuing symptoms for 6-8 weeks, are unlikely to have Lyme disease."[1] and the "unproven and very improbable assumption that chronic B. burgdorgeri infection can occur in the absence of antibodies against B. burgdorferi in serum." [2]
Examples of false Seronegativity are extensively documented on their website, including papers published by authors of the IDSA treatment guidelines.[3][4]
Controversy exists as to the existence of "chronic Lyme disease", with some advocating for the use of long term antibiotics for treatment of a postulated persistent infection. However, the assumption that there is a persistent infection is not supported by high quality clinical evidence, and the use of long term antibiotics is not recommended.[2] However, patient advocacy organizations, as well as the Center for Science in the Public Interest support the ILADS position.[citation needed] Major US medical authorities, including the Infectious Diseases Society of America, the American Academy of Neurology, and the National Institutes of Health, have stated that there is no convincing evidence that Borrelia is involved in chronic Lyme disease. ILADS has questioned the generalizability and reliability of some of the trials referred to by IDSA and the reliability of the current diagnostic tests.[5]
As a result of this fundamentally different view of the nature of long-term effects of Borrelia infection, ILADS has produced treatment recommendations which conflict with those of major mainstream medical bodies. A 2004 article in the Pediatric Infectious Disease Journal on the prevalence of inaccurate online information about Lyme disease cited the ILADS website as a source of such inaccurate material.[6]
References
- ^ Wormser GP; et al. "Clinical practice guidelines by the IDSA"".
{{cite journal}}: Cite journal requires|journal=(help); Explicit use of et al. in:|author=(help); Text "Clin Infect Dis. 2006 Nove 1;43(9):1089-134. Epub 2006 Oct 2" ignored (help) - ^ a b Feder HM, Johnson BJ, O'Connell S; et al. (2007). "A critical appraisal of "chronic Lyme disease"". N. Engl. J. Med. 357 (14): 1422–30. doi:10.1056/NEJMra072023. PMID 17914043.
{{cite journal}}: Explicit use of et al. in:|author=(help); Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ Breier F, Khanakah G, Stanek G; et al. "Isolation and PCR typing of B afzelii from a skin lesion in a seronegative patient".
{{cite journal}}: Cite journal requires|journal=(help); Explicit use of et al. in:|author=(help); Text "Br J Dermatol. 2001 Feb;144(2):387-92" ignored (help)CS1 maint: multiple names: authors list (link) - ^ "Lyme disease associated with fibromylagia".
{{cite journal}}: Cite journal requires|journal=(help); Text "Dinerman H, Steere AC" ignored (help) - ^ Stricker RB (2007). "Counterpoint: long-term antibiotic therapy improves persistent symptoms associated with Lyme disease". Clinical Infectious Diseases. 45 (2): 149–57. doi:10.1086/518853. PMID 17578772.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Cooper JD, Feder HM (2004). "Inaccurate information about lyme disease on the internet" (PDF). Pediatr. Infect. Dis. J. 23 (12): 1105–8. PMID 15626946.
{{cite journal}}: Unknown parameter|month=ignored (help)
External links
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