Viridicatumtoxin B: Difference between revisions
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'''Viridicatumtoxin B''' is a [[fungus]]-derived [[tetracycline]] [[antibiotic]] discovered in 2008. It was isolated from small amounts of [[penicillium]] fungi. A synthetic structure matching that of natural viridicatumtoxin B makes possible synthetic variants that match or surpass its antibiotic potency.<ref name=rd1408>[http://www.rdmag.com/news/2014/08/synthesis-produces-new-antibiotic]</ref> |
'''Viridicatumtoxin B''' is a [[fungus]]-derived [[tetracycline]] [[antibiotic]] discovered in 2008. It was isolated from small amounts of [[penicillium]] fungi. A synthetic structure matching that of natural viridicatumtoxin B makes possible synthetic variants that match or surpass its antibiotic potency.<ref name=rd1408>[http://www.rdmag.com/news/2014/08/synthesis-produces-new-antibiotic]</ref> |
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Revision as of 05:23, 31 August 2014
Viridicatumtoxin B is a fungus-derived tetracycline antibiotic discovered in 2008. It was isolated from small amounts of penicillium fungi. A synthetic structure matching that of natural viridicatumtoxin B makes possible synthetic variants that match or surpass its antibiotic potency.[1]
Analogs lacking a hydroxyl group were even more effective than the original against Gram-positive bacteria.[1]
Concerns about solubility, biodegradation, availability and other issues must be resolved before clinical development begins.[1]