Talk:Mitochondrial replacement therapy

NPOV

Please explain what the potential benefits of this procedure would be. Obviously there must be some, or at least some claimed, or else nobody would be trying to do it. Borock (talk) 04:27, 29 June 2013 (UTC)

An NPOV was an odd tag choice, I'm pulling it. The procedure is notable on its face. Nevertheless, the potential benefits are written into the article - eggs are removed from cells with faulty miochondrials and put into hollowed-out donor eggs. This removes the risk of some inheritable diseases. EBY (talk) 07:51, 29 June 2013 (UTC)

The article didn't give that information when I tagged it. I agree that the topic is notable. I was only asking that the article give both sides of the controversy. Borock (talk) 16:33, 29 June 2013 (UTC)

I will find the info and add it, rather than put back the tag. Borock (talk) 16:37, 29 June 2013 (UTC)

Use a neutral name

The "pronuclei transfer" medical technique is surely notable, so it is right that there is an article about it. But the current name of this article, "three-parent baby", is not neutral. The word "parent" has an order of magnitude more connotations than the term "genetic parent". I know who my parents are. I presume they are also my genetic parents, but I've never actually asked - because I don't care.

Opponents of the technique are trying to popularize the term "three-parent baby" because they believe it has more negative connotations. The article talks about the possibility of "psychological damage" to the babies in question, but the tactics of these people will have the effect of making that psychological damage more likely, in what reminds me of a self-fulfilling prophecy. They would presumably like to rename the extra-marital sex article to bastard--child, but they have lost the battle to stigmatize children of unmarried parents, so are fighting new battles instead. Open4D (talk) 22:58, 27 February 2014 (UTC)

Could the donor of the nuclear DNA for the egg be male?

Would it work if a woman supplied the mitrochondrial DNA and egg, but the donor of the nuclear DNA for the egg were male? Because the mitochondrial DNA is a relatively minor player, this would allow two men to have a baby that was mostly their DNA. 216.66.5.43 (talk) 12:47, 11 March 2014 (UTC)

I believe the whole nucleus of the mother is put into a donor egg. The nucleus is from the mother's egg, so I don't believe the nucleus of a man's cell could be used. 96.243.136.117 (talk) 06:16, 29 March 2014 (UTC)

"but none have yet been brought to term.[5]" is incorrect

I came here upon Google search for mitochondrial dna in vitro. The BBC News hour at 9 AM CDT USA interviewed a woman born in the 90's when the practice was done. It mentioned that quite a few people alive have triple DNA. They DID mention many were born with or experienced problems, implying a high ratio, in babies born, of relative failure to apparent success. It also said that (in my words) "the experiment is incomplete" in that this triple DNA is going to be passed down to future generations!

URL: BBC new story "The girl with three biological parents" - contains the line "Seventeen babies were born at Cohen's clinic, as a result of cytoplasmic transfer, who could have had DNA from three people."

WardXmodem (talk) 16:01, 1 September 2014 (UTC)