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Burow's solution, named after the mid-19th century ophthalmologist Karl August Burow, is a pharmacological preparation comprising an aqueous solution of aluminium acetate. It is available in the U.S. as an over the counter preparation, with brand-names including Domeboro, Domeboro Otic, Star-Otic, and Borofair.^[1] The preparation has astringent and antibacterial properties and may be used to treat a number of skin conditions such as insect bites, rashes caused by poison ivy and poison sumac, swelling, allergies and bruises. However its principal use is as a treatment for otitis, including otomycosis.^[2]

Otitis

Burow's solution may be used to treat various forms of otitis.^[3]^[4] As a drug it is inexpensive and non-ototoxic. In cases of otomycosis it is less effective than clotrimazole but remains an effective treatment.^[5]

Off-Label Usages

Many consumers have found off-label usages for products derived from Burow's solution. Due to the strength of the solution, some use it to treat ingrown nails, where products derived from Burow's solution such as Domeboro are used in combination with warm water to help consumers contain the infection.^[6]

References

^ Drugs.com: Acetic acid/ aluminum acetate solution
^ Thorp; Kruger, J.; Oliver, S.; Nilssen, E. L. K.; Prescott, C. A. J.; et al. (1998). "The antibacterial activity of acetic acid and Burow's solution as topical otological preparations". J. Laryngology & Otology. 112 (112). Cambridge University Press: 925–928. doi:10.1017/S0022215100142100. {{cite journal}}: Explicit use of et al. in: |author= (help)
^ Kashiwamura M, Chida E, Matsumura M, Nakamaru Y, Suda N, Terayama Y, Fukuda S (January 2004). "The efficacy of Burow's solution as an ear preparation for the treatment of chronic ear infections". Otology & Neurotology. 25 (1): 9–13. doi:10.1097/00129492-200401000-00002. PMID 14724484. Retrieved 2013-05-18.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ Kashiwamura, Masaaki; Chida, Eiji; Matsumura, Michiya; Nakamaru, Yuuji; Suda, Noriyuki; Terayama, Yoshihiko; Fukuda, Satoshi. "The Efficacy of Burow's Solution as an Ear Preparation for the Treatment of Chronic Ear Infections". Otology & Neurotology. 25 (1): 9–13. doi:10.1097/00129492-200401000-00002.
^ Munguia, Raymundo; Daniel, Sam J. "Ototopical antifungals and otomycosis: A review". International Journal of Pediatric Otorhinolaryngology. 72 (4): 453–459. doi:10.1016/j.ijporl.2007.12.005.
^ http://www.nytimes.com/health/guides/symptoms/foot-pain/ingrown-toenails.html

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[1] Drugs.com: Acetic acid/ aluminum acetate solution

[Thorp,_1998-2] Thorp; Kruger, J.; Oliver, S.; Nilssen, E. L. K.; Prescott, C. A. J.; et al. (1998). "The antibacterial activity of acetic acid and Burow's solution as topical otological preparations". J. Laryngology & Otology. 112 (112). Cambridge University Press: 925–928. doi:10.1017/S0022215100142100. {{cite journal}}: Explicit use of et al. in: |author= (help)

[3] Kashiwamura M, Chida E, Matsumura M, Nakamaru Y, Suda N, Terayama Y, Fukuda S (January 2004). "The efficacy of Burow's solution as an ear preparation for the treatment of chronic ear infections". Otology & Neurotology. 25 (1): 9–13. doi:10.1097/00129492-200401000-00002. PMID 14724484. Retrieved 2013-05-18.{{cite journal}}: CS1 maint: multiple names: authors list (link)

[4] Kashiwamura, Masaaki; Chida, Eiji; Matsumura, Michiya; Nakamaru, Yuuji; Suda, Noriyuki; Terayama, Yoshihiko; Fukuda, Satoshi. "The Efficacy of Burow's Solution as an Ear Preparation for the Treatment of Chronic Ear Infections". Otology & Neurotology. 25 (1): 9–13. doi:10.1097/00129492-200401000-00002.

[5] Munguia, Raymundo; Daniel, Sam J. "Ototopical antifungals and otomycosis: A review". International Journal of Pediatric Otorhinolaryngology. 72 (4): 453–459. doi:10.1016/j.ijporl.2007.12.005.

[6] ttp://www.nytimes.com/health/guides/symptoms/foot-pain/ingrown-toenails.html

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@@ Line 25: / Line 25: @@
 Burow's solution may be used to treat various forms of [[otitis]].<ref>{{cite journal |author=Kashiwamura M, Chida E, Matsumura M, Nakamaru Y, Suda N, Terayama Y, Fukuda S |title=The efficacy of Burow's solution as an ear preparation for the treatment of chronic ear infections |journal=Otology & Neurotology |volume=25 |issue=1 |pages=9–13 |date=January 2004 |pmid=14724484 |doi= 10.1097/00129492-200401000-00002|url=http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=1531-7129&volume=25&issue=1&spage=9 |accessdate=2013-05-18}}</ref><ref>{{cite journal|last1=Kashiwamura|first1=Masaaki|last2=Chida|first2=Eiji|last3=Matsumura|first3=Michiya|last4=Nakamaru|first4=Yuuji|last5=Suda|first5=Noriyuki|last6=Terayama|first6=Yoshihiko|last7=Fukuda|first7=Satoshi|title=The Efficacy of Burow's Solution as an Ear Preparation for the Treatment of Chronic Ear Infections|journal=Otology & Neurotology|volume=25|issue=1|pages=9–13|doi=10.1097/00129492-200401000-00002}}</ref> As a drug it is inexpensive and [[ototoxicity|non-ototoxic]]. In cases of [[otomycosis]] it is less effective than [[clotrimazole]] but remains an effective treatment.<ref>{{cite journal|last1=Munguia|first1=Raymundo|last2=Daniel|first2=Sam J.|title=Ototopical antifungals and otomycosis: A review|journal=International Journal of Pediatric Otorhinolaryngology|volume=72|issue=4|pages=453–459|doi=10.1016/j.ijporl.2007.12.005}}</ref>
+==Off-Label Usages==
+Many consumers have found off-label usages for products derived from Burow's solution. Due to the strength of the solution, some use it to treat ingrown nails, where products derived from Burow's solution such as Domeboro are used in combination with warm water to help consumers contain the infection.<ref>http://www.nytimes.com/health/guides/symptoms/foot-pain/ingrown-toenails.html</ref>
 ==See also==
 * [[Urushiol]]