P2Y12: Difference between revisions
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'''P2Y12''' is a [[chemoreceptor]] for [[adenosine diphosphate]] (ADP) found on the cell surface of [[blood]] [[platelet]] cells. It is an important regulator in blood platelet coagulation. The drug [[Clopidogrel]] binds to this receptor and is marketed as a platelet anticoagulant. In an April 2006 article, a team of researchers published a study of the role of platelet-transported [[serotonin]] in [[liver]] regeneration, in which this method of platelet anticoagulant therapy was used [http://www.sciencemag.org/cgi/content/full/312/5770/104]. |
'''P2Y12''' is a [[chemoreceptor]] for [[adenosine diphosphate]] (ADP) found on the cell surface of [[blood]] [[platelet]] cells. It is an important regulator in blood platelet coagulation. The drug [[Clopidogrel]] binds to this receptor and is marketed as a platelet anticoagulant. In an April 2006 article, a team of researchers published a study of the role of platelet-transported [[serotonin]] in [[liver]] regeneration, in which this method of platelet anticoagulant therapy was used [http://www.sciencemag.org/cgi/content/full/312/5770/104]. |
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==External links== |
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*[http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2402 IUPHAR GPCR Database - P2Y<sub>12</sub> Receptor] |
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Revision as of 10:00, 21 July 2006
 | This article provides insufficient context for those unfamiliar with the subject. |
P2Y12 is a chemoreceptor for adenosine diphosphate (ADP) found on the cell surface of blood platelet cells. It is an important regulator in blood platelet coagulation. The drug Clopidogrel binds to this receptor and is marketed as a platelet anticoagulant. In an April 2006 article, a team of researchers published a study of the role of platelet-transported serotonin in liver regeneration, in which this method of platelet anticoagulant therapy was used [1].